A Bayesian Survival Model for Time-Varying Coefficients and Unobserved Heterogeneity

التفاصيل البيبلوغرافية
العنوان: A Bayesian Survival Model for Time-Varying Coefficients and Unobserved Heterogeneity
المؤلفون: Knaus, Peter, Winkler, Daniel, Jomrich, Gerd
سنة النشر: 2022
مصطلحات موضوعية: Statistics - Methodology, Statistics - Computation, 62N02, G.3
الوصف: Dynamic survival models are a flexible tool for overcoming limitations of popular methods in the field of survival analysis. While this flexibility allows them to uncover more intricate relationships between covariates and the time-to-event, it also has them running the risk of overfitting. This paper proposes a solution to this issue based on state of the art global-local shrinkage priors and shows that they are able to effectively regularize the amount of time-variation observed in the parameters. Further, a novel approach to accounting for unobserved heterogeneity in the data through a dynamic factor model is introduced. An efficient MCMC sampler is developed and made available in an accompanying R package. Finally, the method is applied to a current data set of survival times of patients with adenocarcinoma of the gastroesophageal junction.
Comment: 19 pages, 3 figures, 2 tables
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2206.11320
رقم الأكسشن: edsarx.2206.11320
قاعدة البيانات: arXiv