تقرير
Multiphase Field Model of Cells on a Substrate
| العنوان: | Multiphase Field Model of Cells on a Substrate |
|---|---|
| المؤلفون: | Chiang, Michael, Hopkins, Austin, Loewe, Benjamin, Marenduzzo, Davide, Marchetti, M. Cristina |
| سنة النشر: | 2024 |
| المجموعة: | Condensed Matter Physics (Other) |
| مصطلحات موضوعية: | Condensed Matter - Soft Condensed Matter, Physics - Biological Physics |
| الوصف: | Multiphase field models have emerged as an important computational tool for understanding biological tissue while resolving single-cell properties. While they have successfully reproduced many experimentally observed behaviors of living tissue, the theoretical underpinnings have not been fully explored. We show that a two-dimensional version of the model, which is commonly employed to study tissue monolayers, can be derived from a three-dimensional version in the presence of a substrate. We also show how viscous forces, which arise from friction between different cells, can be included in the model. Finally, we numerically simulate a tissue monolayer, and find that intercellular friction tends to solidify the tissue. Comment: 14 pages, 2 figures |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/2403.10715 |
| رقم الأكسشن: | edsarx.2403.10715 |
| قاعدة البيانات: | arXiv |
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