تقرير
A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number
| العنوان: | A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number |
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| المؤلفون: | Belluccini, Giulia, Lin, Qianying, Williams, Bevelynn, Lou, Yijun, Vatansever, Zati, López-García, Martín, Lythe, Grant, Leitner, Thomas, Romero-Severson, Ethan, Molina-París, Carmen |
| سنة النشر: | 2024 |
| المجموعة: | Quantitative Biology |
| مصطلحات موضوعية: | Quantitative Biology - Populations and Evolution, Quantitative Biology - Quantitative Methods |
| الوصف: | With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral strains, resident and invasive, and under the assumption that co-feeding is the only transmission route in a tick population, the invasion reproduction number depends on whether the model system of ordinary differential equations possesses the property of neutrality. We show that a simple model, with two populations of ticks infected with one strain, resident or invasive, and one population of co-infected ticks, does not have Alizon's neutrality property. We present model alternatives that are capable of representing the invasion potential of a novel strain by including populations of ticks dually infected with the same strain. The invasion reproduction number is analysed with the next-generation method and via numerical simulations. Comment: 37 pages and 4 figures |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/2403.15282 |
| رقم الأكسشن: | edsarx.2403.15282 |
| قاعدة البيانات: | arXiv |
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