تقرير
Deformable MRI Sequence Registration for AI-based Prostate Cancer Diagnosis
| العنوان: | Deformable MRI Sequence Registration for AI-based Prostate Cancer Diagnosis |
|---|---|
| المؤلفون: | Hering, Alessa, de Boer, Sarah, Saha, Anindo, Twilt, Jasper J., Heinrich, Mattias P., Yakar, Derya, de Rooij, Maarten, Huisman, Henkjan, Bosma, Joeran S. |
| سنة النشر: | 2024 |
| المجموعة: | Computer Science Quantitative Biology |
| مصطلحات موضوعية: | Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition, Quantitative Biology - Quantitative Methods |
| الوصف: | The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and diffusion-weighted scans. These scans can be misaligned due to multiple factors in the scanning process. Image registration can alleviate this issue by predicting the deformation between the sequences. We investigate the effect of image registration on the diagnostic performance of AI-based prostate cancer diagnosis. First, the image registration algorithm, developed in MeVisLab, is analyzed using a dataset with paired lesion annotations. Second, the effect on diagnosis is evaluated by comparing case-level cancer diagnosis performance between using the original dataset, rigidly aligned diffusion-weighted scans, or deformably aligned diffusion-weighted scans. Rigid registration showed no improvement. Deformable registration demonstrated a substantial improvement in lesion overlap (+10% median Dice score) and a positive yet non-significant improvement in diagnostic performance (+0.3% AUROC, p=0.18). Our investigation shows that a substantial improvement in lesion alignment does not directly lead to a significant improvement in diagnostic performance. Qualitative analysis indicated that jointly developing image registration methods and diagnostic AI algorithms could enhance diagnostic accuracy and patient outcomes. |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/2404.09666 |
| رقم الأكسشن: | edsarx.2404.09666 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |