Parameter estimation in ODEs: assessing the potential of local and global solvers

التفاصيل البيبلوغرافية
العنوان: Parameter estimation in ODEs: assessing the potential of local and global solvers
المؤلفون: de Dios, M. Fernández, González-Rueda, Ángel M., Banga, Julio R., González-Díaz, Julio, Penas, David R.
سنة النشر: 2024
المجموعة: Mathematics
Quantitative Biology
مصطلحات موضوعية: Mathematics - Optimization and Control, Quantitative Biology - Quantitative Methods, 90C26
الوصف: We consider the problem of parameter estimation in dynamic systems described by ordinary differential equations. A review of the existing literature emphasizes the need for deterministic global optimization methods due to the nonconvex nature of these problems. Recent works have focused on expanding the capabilities of specialized deterministic global optimization algorithms to handle more complex problems. Despite advancements, current deterministic methods are limited to problems with a maximum of around five state and five decision variables, prompting ongoing efforts to enhance their applicability to practical problems. Our study seeks to assess the effectiveness of state-of-the-art general-purpose global and local solvers in handling realistic-sized problems efficiently, and evaluating their capabilities to cope with the nonconvex nature of the underlying estimation problems.
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2405.01989
رقم الأكسشن: edsarx.2405.01989
قاعدة البيانات: arXiv