تقرير
Mathematical models of the Arabidopsis circadian oscillator
| العنوان: | Mathematical models of the Arabidopsis circadian oscillator |
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| المؤلفون: | Henao, Lucas, Ares, Saúl, Catalán, Pablo |
| المصدر: | Biophysica 4 (2024) 267-282 |
| سنة النشر: | 2024 |
| المجموعة: | Nonlinear Sciences Physics (Other) Quantitative Biology |
| مصطلحات موضوعية: | Physics - Biological Physics, Nonlinear Sciences - Pattern Formation and Solitons, Quantitative Biology - Molecular Networks |
| الوصف: | We review the construction and evolution of mathematical models of the Arabidopsis circadian clock, structuring the discussion into two distinct historical phases of modeling strategies: extension and reduction. The extension phase explores the bottom-up assembly of regulatory networks introducing as many components and interactions as possible in order to capture the oscillatory nature of the clock. The reduction phase deals with functional decomposition, distilling complex models to their essential dynamical repertoire. Current challenges in this field, including the integration of spatial considerations and environmental influences like light and temperature, are also discussed. The review emphasizes the ongoing need for models that balance molecular detail with practical simplicity. |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.3390/biophysica4020019 |
| URL الوصول: | http://arxiv.org/abs/2405.18006 |
| رقم الأكسشن: | edsarx.2405.18006 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.3390/biophysica4020019 |
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