Geo-UNet: A Geometrically Constrained Neural Framework for Clinical-Grade Lumen Segmentation in Intravascular Ultrasound

التفاصيل البيبلوغرافية
العنوان: Geo-UNet: A Geometrically Constrained Neural Framework for Clinical-Grade Lumen Segmentation in Intravascular Ultrasound
المؤلفون: Chen, Yiming, D'Souza, Niharika S., Mandepally, Akshith, Henninger, Patrick, Kashyap, Satyananda, Karani, Neerav, Dey, Neel, Zachary, Marcos, Rizq, Raed, Chouinard, Paul, Golland, Polina, Syeda-Mahmood, Tanveer F.
سنة النشر: 2024
المجموعة: Computer Science
مصطلحات موضوعية: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
الوصف: Precisely estimating lumen boundaries in intravascular ultrasound (IVUS) is needed for sizing interventional stents to treat deep vein thrombosis (DVT). Unfortunately, current segmentation networks like the UNet lack the precision needed for clinical adoption in IVUS workflows. This arises due to the difficulty of automatically learning accurate lumen contour from limited training data while accounting for the radial geometry of IVUS imaging. We propose the Geo-UNet framework to address these issues via a design informed by the geometry of the lumen contour segmentation task. We first convert the input data and segmentation targets from Cartesian to polar coordinates. Starting from a convUNet feature extractor, we propose a two-task setup, one for conventional pixel-wise labeling and the other for single boundary lumen-contour localization. We directly combine the two predictions by passing the predicted lumen contour through a new activation (named CDFeLU) to filter out spurious pixel-wise predictions. Our unified loss function carefully balances area-based, distance-based, and contour-based penalties to provide near clinical-grade generalization in unseen patient data. We also introduce a lightweight, inference-time technique to enhance segmentation smoothness. The efficacy of our framework on a venous IVUS dataset is shown against state-of-the-art models.
Comment: Accepted into the 15th workshop on Machine Learning in Medical Imaging at MICCAI 2024. (* indicates equal contribution)
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2408.04826
رقم الأكسشن: edsarx.2408.04826
قاعدة البيانات: arXiv