دورية أكاديمية
Antioxidant Activity of Panax ginseng to Regulate ROS in Various Chronic Diseases
| العنوان: | Antioxidant Activity of Panax ginseng to Regulate ROS in Various Chronic Diseases |
|---|---|
| المؤلفون: | Md Niaj Morshed, Jong Chan Ahn, Ramya Mathiyalagan, Esrat Jahan Rupa, Reshmi Akter, Md. Rezaul Karim, Dae Hyo Jung, Dong Uk Yang, Deok Chun Yang, Seok Kyu Jung |
| المصدر: | Applied Sciences, Vol 13, Iss 5, p 2893 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Technology LCC:Engineering (General). Civil engineering (General) LCC:Biology (General) LCC:Physics LCC:Chemistry |
| مصطلحات موضوعية: | ROS, antioxidant, oxidative stress, Panax ginseng, ginsenosides, secondary metabolites, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999 |
| الوصف: | Reactive oxygen species (ROS)-the byproduct of regular cell activity formed by various cellular components—play a significant role in pathological and physiological conditions. Alternatively, antioxidants are compounds that reduce or scavenge reactive species in cells. An asymmetry between the antioxidant defense system and ROS from intracellular and extracellular sources cause chronic diseases such as cancer, inflammation, tumorigenesis, cardiovascular and neurogenerative diseases. However, Panax ginseng and its secondary metabolites (known as ginsenosides, phenolic compounds, peptides, acid polysaccharides, polyacetylene, and alkaloids) are well-recognized as antioxidants in many in vitro and in vivo experiments which show beneficial activity in regulating ROS in these diseases. There are extensive evidences that P. ginseng can destroy cancer cells specifically by increasing oxidative stress through ROS generation without significantly harming normal cells. Additionally, numerous studies have examined the antioxidant activity of ginseng and its derivatives on ROS-mediated signaling pathways which are discussed herein. This review summarizes the potential antioxidant activity of P. ginseng in several chronic diseases, and gives updated research evidence with related mechanisms and the future possibilities of nano-formulated compounds of P. ginseng and other polyphenols. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-3417 37610511 |
| Relation: | https://www.mdpi.com/2076-3417/13/5/2893; https://doaj.org/toc/2076-3417 |
| DOI: | 10.3390/app13052893 |
| URL الوصول: | https://doaj.org/article/c0256446e827467faa376105111b8977 |
| رقم الأكسشن: | edsdoj.0256446e827467faa376105111b8977 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder كن أول من يترك تعليقا!