Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma

التفاصيل البيبلوغرافية
العنوان:	Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma
المؤلفون:	Dan Su, Dadong Zhang, Jiaoyue Jin, Lisha Ying, Miao Han, Kaiyan Chen, Bin Li, Junzhou Wu, Zhenghua Xie, Fanrong Zhang, Yihui Lin, Guoping Cheng, Jing-Yu Li, Minran Huang, Jinchao Wang, Kailai Wang, Jianjun Zhang, Fugen Li, Lei Xiong, Andrew Futreal, Weimin Mao
المصدر:	Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
بيانات النشر:	Nature Portfolio, 2019.
سنة النشر:	2019
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Predicting the drug response of patients with cancer is crucial for implementing targeted therapy. Here, Su et al. make patient-derived cell lines and perform targeted sequencing and RNA-seq to identify CDKN2A/2B loss as a predictor of response to CDK4/6 inhibitors in esophageal squamous cell carcinoma.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-019-12846-7
URL الوصول:	https://doaj.org/article/03e2472bfffe4d77bb873151b95d70ea
رقم الأكسشن:	edsdoj.03e2472bfffe4d77bb873151b95d70ea
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-019-12846-7