دورية أكاديمية
Crystal structure of (3S*,4R*)-4-fluoro-3-(4-methoxyphenyl)-1-oxo-2-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
| العنوان: | Crystal structure of (3S*,4R*)-4-fluoro-3-(4-methoxyphenyl)-1-oxo-2-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid |
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| المؤلفون: | Anna Lehmann, Lisa Lechner, Krzysztof Radacki, Holger Braunschweig, Ulrike Holzgrabe |
| المصدر: | Acta Crystallographica Section E: Crystallographic Communications, Vol 73, Iss 6, Pp 867-870 (2017) |
| بيانات النشر: | International Union of Crystallography, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Crystallography |
| مصطلحات موضوعية: | crystal structure, cis conformation, fluorination, 1-oxotetrahydroisoquinolinon-4-carboxylic acid, hydrogen bonding, Crystallography, QD901-999 |
| الوصف: | The title compound, C23H18FNO4, crystallized as a racemate. It exhibits a cis conformation with respect to the F atom and the methine H atom. The piperidine ring has a screw-boat conformation. The methoxyphenyl ring and the phenyl ring are inclined to the mean plane of the isoquinoline ring system by 89.85 (4) and 46.62 (5)°, respectively, and by 78.15 (5)° to one another. In the crystal, molecules are linked by an O—H...O hydrogen bond forming chains propagating along the a-axis direction. The chains are linked by C—H...F hydrogen bonds, forming layers lying parallel to the ab plane. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2056-9890 20569890 |
| Relation: | http://scripts.iucr.org/cgi-bin/paper?S2056989017007186; https://doaj.org/toc/2056-9890 |
| DOI: | 10.1107/S2056989017007186 |
| URL الوصول: | https://doaj.org/article/05515cea89c442f5b10cdea6f9abdab9 |
| رقم الأكسشن: | edsdoj.05515cea89c442f5b10cdea6f9abdab9 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20569890 |
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| DOI: | 10.1107/S2056989017007186 |