دورية أكاديمية

Growth and developmental outcomes of infants with hypoxic ischemic encephalopathy

التفاصيل البيبلوغرافية
العنوان: Growth and developmental outcomes of infants with hypoxic ischemic encephalopathy
المؤلفون: Joonsik Park, Sook Hyun Park, Chloe Kim, So Jin Yoon, Joo Hee Lim, Jung Ho Han, Jeong Eun Shin, Ho Seon Eun, Min Soo Park, Soon Min Lee
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract Despite advances in obstetric care, hypoxic ischemic encephalopathy (HIE) remains a significant disease burden. We determined the national trends of HIE prevalence, therapeutic hypothermia (TH) use, mortality, and outcomes from 2012 to 2019. This study included term infants diagnosed with HIE between 2012 and 2019 from the National Health Insurance Service database. The prevalence of HIE was 2.4 per 1000 births without significant change during the period. TH was performed in approximately 6.7% of infants with HIE, and the annual variation ranged from 2.4 to 12.5%. The mortality among all term infants with HIE was 4.6%. The mortality rate among infants with HIE and TH significantly declined from 40 to 16.9% during the eight years. Infants with TH had higher mortality, increased use of inhaled nitric oxide, and more invasive ventilator use, indicating greater disease severity in the TH group. Infants with TH also showed significantly poorer outcomes, including delayed development, cerebral palsy, sensorineural hearing loss, and seizure, compared to infants without TH (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-023-50187-0
URL الوصول: https://doaj.org/article/d07710aad40544afa14dbe14b983e176
رقم الأكسشن: edsdoj.07710aad40544afa14dbe14b983e176
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-50187-0