دورية أكاديمية

Lumbar neuropathic pain of lower limbs treated by spinal infusion of ziconotide a case – report

التفاصيل البيبلوغرافية
العنوان: Lumbar neuropathic pain of lower limbs treated by spinal infusion of ziconotide a case – report
المؤلفون: Luca Quadrino
المصدر: Pathos, Vol 15, Iss 3, Pp 27-29 (2008)
بيانات النشر: Publiediting, 2008.
سنة النشر: 2008
المجموعة: LCC:Anesthesiology
LCC:Therapeutics. Pharmacology
مصطلحات موضوعية: Severe lumbar pain, ziconotide, intrathecal infusion, Anesthesiology, RD78.3-87.3, Therapeutics. Pharmacology, RM1-950
الوصف: The Author reports the case of a patient with severe lumbar pain unresponsive to NSAIDs. Initial treatment with tramadol gave poor results and a new protocol with hydromorphone – pregabalin was started. The analgesic response was observed only following high hydromorphone doses, associated with unacceptable side effects. A spinal device for continuous intrathecal infusion was then implanted, in order to administer ziconotide, a new opioid drug. Associated therapy included hydromorphone – pregabalin. At the 4 mcg/die dose ziconotide resulted highly effective (with a VAS reduction pain 6-7 to 2-3) even at 1st day after implantation; in addition at day 10, opioid dose was strongly reduced and pregabalin withdrawn. The treatment was associated with a good tolerability. The encouraging results prompted the Author to test ziconotide in further cases of severe chronic pain.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Italian
تدمد: 1593-2354
Relation: http://www.pathos-journal.com/doc/2008_3_Casi_Quadrino.pdf; https://doaj.org/toc/1593-2354
URL الوصول: https://doaj.org/article/0ed700332e4b49ad8e702847f9c73ab6
رقم الأكسشن: edsdoj.0ed700332e4b49ad8e702847f9c73ab6
قاعدة البيانات: Directory of Open Access Journals