دورية أكاديمية
Bacterial α-Glucan and Branching Sucrases from GH70 Family: Discovery, Structure–Function Relationship Studies and Engineering
العنوان: | Bacterial α-Glucan and Branching Sucrases from GH70 Family: Discovery, Structure–Function Relationship Studies and Engineering |
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المؤلفون: | Manon Molina, Gianluca Cioci, Claire Moulis, Etienne Séverac, Magali Remaud-Siméon |
المصدر: | Microorganisms, Vol 9, Iss 8, p 1607 (2021) |
بيانات النشر: | MDPI AG, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Biology (General) |
مصطلحات موضوعية: | glucansucrase, branching sucrase, GH70, lactic acid bacteria, sucrose-active enzymes, Biology (General), QH301-705.5 |
الوصف: | Glucansucrases and branching sucrases are classified in the family 70 of glycoside hydrolases. They are produced by lactic acid bacteria occupying very diverse ecological niches (soil, buccal cavity, sourdough, intestine, dairy products, etc.). Usually secreted by their producer organisms, they are involved in the synthesis of α-glucans from sucrose substrate. They contribute to cell protection while promoting adhesion and colonization of different biotopes. Dextran, an α-1,6 linked linear α-glucan, was the first microbial polysaccharide commercialized for medical applications. Advances in the discovery and characterization of these enzymes have remarkably enriched the available diversity with new catalysts. Research into their molecular mechanisms has highlighted important features governing their peculiarities thus opening up many opportunities for engineering these catalysts to provide new routes for the transformation of sucrose into value-added molecules. This article reviews these different aspects with the ambition to show how they constitute the basis for promising future developments. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2076-2607 |
Relation: | https://www.mdpi.com/2076-2607/9/8/1607; https://doaj.org/toc/2076-2607 |
DOI: | 10.3390/microorganisms9081607 |
URL الوصول: | https://doaj.org/article/1a19d9cb423c4f949210d5f7702de2b4 |
رقم الأكسشن: | edsdoj.1a19d9cb423c4f949210d5f7702de2b4 |
قاعدة البيانات: | Directory of Open Access Journals |
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