دورية أكاديمية
Assessing risk factors, mortality, and healthcare utilization associated with Clostridioides difficile infection in four Latin American countries
العنوان: | Assessing risk factors, mortality, and healthcare utilization associated with Clostridioides difficile infection in four Latin American countries |
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المؤلفون: | Holly Yu, Nestor Flaster, Adrian Lopez Casanello, Daniel Curcio |
المصدر: | Brazilian Journal of Infectious Diseases, Vol 25, Iss 1, Pp 101040- (2021) |
بيانات النشر: | Elsevier, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Infectious and parasitic diseases LCC:Microbiology |
مصطلحات موضوعية: | Clostridioides difficile infection, Latin America, Nosocomial infection, Mortality, Length of hospital stay, Risk factors, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502 |
الوصف: | Background: Clostridioides difficile infection (CDI) is the most common cause of healthcare-associated infections in Western countries. Risk factors, mortality, and healthcare utilization for CDI in Latin America are poorly understood. This study assessed risk factors and burden associated with nosocomial CDI in four Latin American countries. Methods: This retrospective, case-control study used databases and medical records from 8 hospitals in Argentina, Brazil, Chile, and Mexico to identify nosocomial CDI cases from 2014 − 2017. Cases were patients aged ≥18 years with diarrhea and a positive CDI test ≥72 h after hospital admission. Two controls (without diarrhea; length of hospital stay [LOS] ≥3 days; admitted ±14 days from case patient; shared same ward) were matched to each case. CDI-associated risk factors were assessed by univariate and multivariable analyses. CDI burden (LOS, in-hospital mortality) was compared between cases and controls. Results: The study included 481 cases and 962 controls. Mean age and sex were similar between cases and controls, but mean Charlson comorbidity index (4.3 vs 3.6; p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1413-8670 |
Relation: | http://www.sciencedirect.com/science/article/pii/S1413867020301677; https://doaj.org/toc/1413-8670 |
DOI: | 10.1016/j.bjid.2020.11.005 |
URL الوصول: | https://doaj.org/article/1cf750407ebb41ff97604d0a725fd2be |
رقم الأكسشن: | edsdoj.1cf750407ebb41ff97604d0a725fd2be |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14138670 |
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DOI: | 10.1016/j.bjid.2020.11.005 |