دورية أكاديمية
Surgical and oncologic outcomes in surgically treated women 80 years and older with endometrioid endometrial cancer as a function of their comorbidities
العنوان: | Surgical and oncologic outcomes in surgically treated women 80 years and older with endometrioid endometrial cancer as a function of their comorbidities |
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المؤلفون: | Abdelrahman AlAshqar, Maddie Ghazarian, Emily M. Webster, Animesh Upadhyay, Masoud Azodi, Peter E. Schwartz, Elena Ratner, Gary Altwerger |
المصدر: | Gynecologic Oncology Reports, Vol 49, Iss , Pp 101240- (2023) |
بيانات النشر: | Elsevier, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Gynecology and obstetrics LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Cancer survival, Comorbidity Index, Older women, Mortality, Postoperative outcomes, Uterine cancer, Gynecology and obstetrics, RG1-991, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Objective: To describe the surgical and oncologic outcomes in surgically treated oldest old women (≥80 years) with endometrioid endometrial cancer as a function of their comorbidities. Methods: In this retrospective cohort study, patients aged 80–99 years who underwent surgical management of stage I endometrioid endometrial cancer between 2006 and 2018 were included. Low- and high-intermediate risk disease was defined using the Gynecologic Oncology Group-99 criteria. The validated, Combined Age-Charlson Comorbidity Index (CA-CCI) was used to quantify comorbidity burden. Logistic regression was used to identify the independent predictors of various surgical and oncologic outcomes. Kaplan-Meier survival analysis was performed to compare survival distributions based on mortality cause and comorbidity status. Results: We identified 64 women who met the eligibility criteria. Median age was 84 years (IQR 80, 94 years). Among oldest old women undergoing a hysterectomy with or without lymph node dissection, women with a CA-CCI score of ≥7 had an 8 times higher risk of postoperative infections compared with oldest old women with a |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2352-5789 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2352578923001091; https://doaj.org/toc/2352-5789 |
DOI: | 10.1016/j.gore.2023.101240 |
URL الوصول: | https://doaj.org/article/1dd4e0249f084913b7d65e5f2adc83a0 |
رقم الأكسشن: | edsdoj.1dd4e0249f084913b7d65e5f2adc83a0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 23525789 |
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DOI: | 10.1016/j.gore.2023.101240 |