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Vitamin D and Bone Health of Older Adults within Care Homes: An Observational Study

التفاصيل البيبلوغرافية
العنوان: Vitamin D and Bone Health of Older Adults within Care Homes: An Observational Study
المؤلفون: Orlagh Feehan, David J. Armstrong, Pamela J. Magee, L. Kirsty Pourshahidi, J. J. Strain, Laura Beggan, Diego F. Cobice, Emeir M. McSorley
المصدر: Nutrients, Vol 14, Iss 13, p 2680 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Nutrition. Foods and food supply
مصطلحات موضوعية: vitamin D deficiency, aged, 80 and over, nursing home, osteoporosis, vitamin D supplementation, Nutrition. Foods and food supply, TX341-641
الوصف: Limited studies have reported vitamin D status and health outcomes in care home residents, a group at risk of vitamin D deficiency. This study investigated serum 25-hydroxyvitamin D (25-OHD) concentrations in older adults within care homes in Northern Ireland (NI) and its association with musculoskeletal health (ultrasound T-score, muscle strength, Timed Up & Go test (TUG)), bone turnover markers (BTMs), and immune function markers. A total of 87 participants were recruited with mean ± SD age 83.2 ± 7.9 years. Mean ± SD serum 25-OHD concentration (n 69) was 49.52 ± 35.58 nmol/L. Vitamin D deficiency (25-OHD n 24) of participants with 17.4% (n 12) classified as insufficient (25-OHD 25–50 nmol/L) and 47.8% (n 33) as sufficient (25-OHD >50 nmol/L). 25-OHD concentration was not an independent predictor of T-score, muscle strength, TUG, or inflammatory cytokines. After adjusting for covariates, a significant negative association was observed between 25-OHD concentration and the BTMs; osteocalcin (β = −0.395; p = 0.001), procollagen type 1 N propeptide (P1NP) (β = −0.320; p = 0.012), and C-terminal telopeptide of type 1 collagen (CTX) (β = −0.377; p = 0.003). Higher 25-OHD concentration was positively associated with use of vitamin D ± calcium supplementation (β = 0.610; p < 0.001). Vitamin D deficiency and insufficiency were highly prevalent in this sample of care home residents in NI. Higher 25-OHD concentration was associated with greater supplement use and with reduced bone turnover, which in this population is linked with reduced bone loss. These findings emphasize the need for a mandatory vitamin D ± calcium supplementation policy specific for care home residents.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 14132680
2072-6643
Relation: https://www.mdpi.com/2072-6643/14/13/2680; https://doaj.org/toc/2072-6643
DOI: 10.3390/nu14132680
URL الوصول: https://doaj.org/article/23821dfac92948168f47b8bfcf4c5f25
رقم الأكسشن: edsdoj.23821dfac92948168f47b8bfcf4c5f25
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14132680
20726643
DOI:10.3390/nu14132680