دورية أكاديمية
The Role of Antibodies in the Treatment of SARS-CoV-2 Virus Infection, and Evaluating Their Contribution to Antibody-Dependent Enhancement of Infection
| العنوان: | The Role of Antibodies in the Treatment of SARS-CoV-2 Virus Infection, and Evaluating Their Contribution to Antibody-Dependent Enhancement of Infection |
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| المؤلفون: | Mohammed A. H. Farouq, Reinaldo Acevedo, Valerie A. Ferro, Paul A. Mulheran, Mohammed M. Al Qaraghuli |
| المصدر: | International Journal of Molecular Sciences, Vol 23, Iss 11, p 6078 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | coronavirus, SARS-CoV-2, antibody-dependent enhancement, COVID-19, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Antibodies play a crucial role in the immune response, in fighting off pathogens as well as helping create strong immunological memory. Antibody-dependent enhancement (ADE) occurs when non-neutralising antibodies recognise and bind to a pathogen, but are unable to prevent infection, and is widely known and is reported as occurring in infection caused by several viruses. This narrative review explores the ADE phenomenon, its occurrence in viral infections and evaluates its role in infection by SARS-CoV-2 virus, which causes coronavirus disease 2019 (COVID-19). As of yet, there is no clear evidence of ADE in SARS-CoV-2, though this area is still subject to further study. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/23/11/6078; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms23116078 |
| URL الوصول: | https://doaj.org/article/e299d18c3cc741cabd1e583a9ab20917 |
| رقم الأكسشن: | edsdoj.299d18c3cc741cabd1e583a9ab20917 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms23116078 |