دورية أكاديمية
Effectiveness of Dermal Regeneration Templates in Managing Acute Full-thickness and Deep Dermal Burn Injuries: A Comparison with Split-thickness Skin Grafts
| العنوان: | Effectiveness of Dermal Regeneration Templates in Managing Acute Full-thickness and Deep Dermal Burn Injuries: A Comparison with Split-thickness Skin Grafts |
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| المؤلفون: | Sarah W. Alkhonizy, MD, Belal Nedal Sabbah, MD, Majd S. Khader, MD, Saleha Abdul Rab, MD, Eman Naeem Chaudhri, MD, Khalid M. Safar Alsofyani, MD, Hiba Muhammad Raheel, MD, Mohamad Alhassoun, MD, Abdulaziz Alabdulkarim, MD, FRCSC |
| المصدر: | Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 2, p e5572 (2024) |
| بيانات النشر: | Wolters Kluwer, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Surgery |
| مصطلحات موضوعية: | Surgery, RD1-811 |
| الوصف: | Background:. The therapeutic challenge of managing acute full-thickness burns is significantly ameliorated with the introduction of dermal regeneration templates (DRTs). However, an updated synthesis of evidence-based data on the efficacy and safety of different DRTs is required. Methods:. This systematic review and meta-analysis conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines aims to evaluate the role of various DRTs in comparison with split-thickness skin grafting in managing acute burn injuries after excision and debridement. A total of 28 randomized clinical trials were assessed, encompassing a wide array of DRTs. Results:. The study outcomes pointed to the diverse effectiveness of DRTs, with Integra demonstrating peripheral nerve reinnervation potential and TransCyte promoting rapid re-epithelialization. Some DRTs showed scar formation and skin quality comparable to those of autologous skin grafts. In terms of wound infection, certain treatments, including TransCyte, exhibited a significantly low infection rate. The evaluation of scar quality suggested that various interventions produced acceptable or improved outcomes without hypertrophic scarring. Recovery rates after the interventions displayed a range, with certain treatments showing rapid recovery and satisfactory results. Conclusions:. The current systematic review points to the potential benefits of DRTs in managing burn wounds. Further research is necessary to shed light on the long-term impacts of these interventions on wound healing, scar quality, and patient recovery. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2169-7574 00000000 |
| Relation: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005572; https://doaj.org/toc/2169-7574 |
| DOI: | 10.1097/GOX.0000000000005572 |
| URL الوصول: | https://doaj.org/article/2b60ed2e06814eac83f1f7947aed4d08 |
| رقم الأكسشن: | edsdoj.2b60ed2e06814eac83f1f7947aed4d08 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21697574 00000000 |
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| DOI: | 10.1097/GOX.0000000000005572 |