دورية أكاديمية
Upregulation of Heme Oxygenase-1 Combined with Increased Adiponectin Lowers Blood Pressure in Diabetic Spontaneously Hypertensive Rats through a Reduction in Endothelial Cell Dysfunction, Apoptosis and Oxidative Stress
| العنوان: | Upregulation of Heme Oxygenase-1 Combined with Increased Adiponectin Lowers Blood Pressure in Diabetic Spontaneously Hypertensive Rats through a Reduction in Endothelial Cell Dysfunction, Apoptosis and Oxidative Stress |
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| المؤلفون: | Jian Cao, George Drummond, Kazuyoshi Inoue, Shinji Omura, Komal Sodhi, Xiao Ying Li |
| المصدر: | International Journal of Molecular Sciences, Vol 9, Iss 12, Pp 2388-2406 (2008) |
| بيانات النشر: | MDPI AG, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | Heme oxygenase, hypertension, diabetes, adiponectin, oxidative stress, apoptosis, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | This study was designed to investigate the effect of increased levels of HO-1 on hypertension exacerbated by diabetes. Diabetic spontaneously hypertensive rat (SHR) and WKY (control) animals were treated with streptozotocin (STZ) to induce diabetes and stannous chloride (SnCl2) to upregulate HO-1. Treatment with SnCl2 not only attenuated the increase of blood pressure (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 |
| Relation: | http://www.mdpi.com/1422-0067/9/12/2388/; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms9122388 |
| URL الوصول: | https://doaj.org/article/2e16b774d643482a864f0a836fb144ef |
| رقم الأكسشن: | edsdoj.2e16b774d643482a864f0a836fb144ef |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 |
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| DOI: | 10.3390/ijms9122388 |