دورية أكاديمية
Does Metformin Affect The Incidence of Colonic Polyps and Adenomas in Patients with Type 2 Diabetes Mellitus?
| العنوان: | Does Metformin Affect The Incidence of Colonic Polyps and Adenomas in Patients with Type 2 Diabetes Mellitus? |
|---|---|
| المؤلفون: | Youn Hee Cho, Bong Min Ko, Shin Hee Kim, Yu Sik Myung, Jong Hyo Choi, Jae Pil Han, Su Jin Hong, Seong Ran Jeon, Hyun Gun Kim, Jin Oh Kim, Moon Sung Lee |
| المصدر: | Intestinal Research, Vol 12, Iss 2, Pp 139-145 (2014) |
| بيانات النشر: | Korean Association for the Study of Intestinal Diseases, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Medicine LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Colon adenoma, Adenoma detection rate, Polyp detection rate, Metformin, Diabetes mellitus, type 2, Medicine, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background/AimsColorectal cancer (CRC) develops from colonic adenomas. Type 2 diabetes mellitus (DM) is associated with a higher risk of CRC and metformin decreases CRC risk. However, it is not certain if metformin affects the development of colorectal polyps and adenomas. This study aimed to elucidate if metforminaffects the incidence of colonic polyps and adenomas in patients with type 2 DM.MethodsOf 12,186 patients with type 2 DM, 3,775 underwent colonoscopy between May 2001 and March 2013. This study enrolled 3,105 of these patients, and divided them in two groups: 912 patients with metformin use and 2,193 patients without metformin use. Patient clinical characteristics, polyp and adenoma detection rate in the two groups were analyzed retrospectively.ResultsThe Colorectal polyp detection rate was lower in the metformin group than in the non-meformin group (39.4% vs. 62.4%, P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1598-9100 2288-1956 |
| Relation: | http://www.irjournal.org/upload/pdf/ir-12-139.pdf; https://doaj.org/toc/1598-9100; https://doaj.org/toc/2288-1956 |
| DOI: | 10.5217/ir.2014.12.2.139 |
| URL الوصول: | https://doaj.org/article/2e7d983f7afb43ec8ae840b2f95efbce |
| رقم الأكسشن: | edsdoj.2e7d983f7afb43ec8ae840b2f95efbce |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15989100 22881956 |
|---|---|
| DOI: | 10.5217/ir.2014.12.2.139 |