دورية أكاديمية

Refining muscle geometry and wrapping in the TLEM 2 model for improved hip contact force prediction.

التفاصيل البيبلوغرافية
العنوان: Refining muscle geometry and wrapping in the TLEM 2 model for improved hip contact force prediction.
المؤلفون: Enrico De Pieri, Morten E Lund, Anantharaman Gopalakrishnan, Kasper P Rasmussen, David E Lunn, Stephen J Ferguson
المصدر: PLoS ONE, Vol 13, Iss 9, p e0204109 (2018)
بيانات النشر: Public Library of Science (PLoS), 2018.
سنة النشر: 2018
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Musculoskeletal models represent a powerful tool to gain knowledge on the internal forces acting at the joint level in a non-invasive way. However, these models can present some errors associated with the level of detail in their geometrical representation. For this reason, a thorough validation is necessary to prove the reliability of their predictions. This study documents the development of a generic musculoskeletal model and proposes a working logic and simulation techniques for identifying specific model features in need of refinement; as well as providing a quantitative validation for the prediction of hip contact forces (HCF). The model, implemented in the AnyBody Modeling System and based on the cadaveric dataset TLEM 2.0, was scaled to match the anthropometry of a patient fitted with an instrumented hip implant and to reproduce gait kinematics based on motion capture data. The relative contribution of individual muscle elements to the HCF and joint moments was analyzed to identify critical geometries, which were then compared to muscle magnetic resonance imaging (MRI) scans and, in case of inconsistencies, were modified to better match the volumetric scans. The predicted HCF showed good agreement with the overall trend and timing of the measured HCF from the instrumented prosthesis. The average root mean square error (RMSE), calculated for the total HCF was found to be 0.298*BW. Refining the geometries of the muscles thus identified reduced RMSE on HCF magnitudes by 17% (from 0.359*BW to 0.298*BW) over the whole gait cycle. The detailed study of individual muscle contributions to the HCF succeeded in identifying muscles with incorrect anatomy, which would have been difficult to intuitively identify otherwise. Despite a certain residual over-prediction of the final hip contact forces in the stance phase, a satisfactory level of geometrical accuracy of muscle paths has been achieved with the refinement of this model.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC6141086?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0204109
URL الوصول: https://doaj.org/article/32677716980344f78f52ee9c32e3ae2d
رقم الأكسشن: edsdoj.32677716980344f78f52ee9c32e3ae2d
قاعدة البيانات: Directory of Open Access Journals