دورية أكاديمية
أعرض في EDS

Daily Usage of Proton Pump Inhibitors May Reduce the Severity of Critical Upper Gastrointestinal Bleeding in Elderly Patients

التفاصيل البيبلوغرافية
العنوان: Daily Usage of Proton Pump Inhibitors May Reduce the Severity of Critical Upper Gastrointestinal Bleeding in Elderly Patients
المؤلفون: Hidetaka Matsuda, Takuto Nosaka, Yu Akazawa, Yasushi Saito, Yoshihiko Ozaki, Kazuto Takahashi, Tatsushi Naito, Kazuya Ofuji, Masahiro Ohtani, Katsushi Hiramatsu, Yasunari Nakamoto
المصدر: Gastroenterology Research and Practice, Vol 2020 (2020)
بيانات النشر: Wiley, 2020.
سنة النشر: 2020
المجموعة: LCC:Diseases of the digestive system. Gastroenterology
مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869
الوصف: Introduction. We retrospectively examined the relationship between daily proton pump inhibitor (PPI) use and severity of upper gastrointestinal bleeding (UGIB), mainly in the elderly. Methods. We included 97 patients with nonvariceal UGIB diagnosed at our hospital from January 2012 to October 2017. Bleeding severity was assessed using the shock index (SI) and estimated bleeding volume; 49 patients met the criterion for the mild group and 48 for the moderate/severe group. The effect of PPI use on bleeding severity was compared between the groups. The relationships of PPI use and dose with the clinical symptoms of UGIB were also analyzed. Results. Among the 97 patients, 17 (17.5%) habitually used PPIs. The rate of habitual PPI use was significantly higher in the mild group, indicating as an independent factor contributing to a reduction in the severity of UGIB in a multiple logistic regression analysis (30.6% vs. 4.2%; OR 10.147; 95% CI 2.174–47.358, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1687-6121
1687-630X
Relation: https://doaj.org/toc/1687-6121; https://doaj.org/toc/1687-630X
DOI: 10.1155/2020/7168621
URL الوصول: https://doaj.org/article/e3936d13ea8e4bdeab5f3ebcf5282e40
رقم الأكسشن: edsdoj.3936d13ea8e4bdeab5f3ebcf5282e40
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16876121
1687630X
DOI:10.1155/2020/7168621