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Association of diabetic ketoacidosis, severe hypoglycemia and glycemic control among children and young adults with type 1 diabetes mellitus treated with premixed versus basal-bolus insulin therapyAt a glance of commentary

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العنوان: Association of diabetic ketoacidosis, severe hypoglycemia and glycemic control among children and young adults with type 1 diabetes mellitus treated with premixed versus basal-bolus insulin therapyAt a glance of commentary
المؤلفون: Wei-Yu Chou, Yan-Rong Li, Wai Kin Chan, Szu-Tah Chen
المصدر: Biomedical Journal, Vol 41, Iss 6, Pp 348-355 (2018)
بيانات النشر: Elsevier, 2018.
سنة النشر: 2018
المجموعة: LCC:Medicine (General)
LCC:Biology (General)
مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5
الوصف: Background: This study compared event rates of diabetic ketoacidosis (DKA) and severe hypoglycemia, as well as glycemic control, among children, adolescents, and young adults with type 1 diabetes mellitus (T1DM) receiving basal-bolus or premixed insulin therapy. Methods: A total of 825 individuals aged ≤ 20 years with T1DM, using either basal-bolus or premixed insulin regimens, were retrospectively recruited from 2001 to 2015. Rates of DKA after diagnosis, severe hypoglycemia, and the level of glycated hemoglobin A1c (HbA1c) improvement during the follow-up period were analyzed. Results: Of the 825 patients, 226 receiving a premixed regimen were matched to the same number of patients receiving a basal-bolus regimen. In the matched cohort, DKA (10.62% vs. 5.31%; p = 0.037) and severe hypoglycemic episodes (25.22% vs. 10.62%; p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2319-4170
Relation: http://www.sciencedirect.com/science/article/pii/S2319417018301847; https://doaj.org/toc/2319-4170
DOI: 10.1016/j.bj.2018.10.005
URL الوصول: https://doaj.org/article/d4017ff4847e43398c45b4ab405ee7d2
رقم الأكسشن: edsdoj.4017ff4847e43398c45b4ab405ee7d2
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23194170
DOI:10.1016/j.bj.2018.10.005