دورية أكاديمية
Salicylanilide Acetates: Synthesis and Antibacterial Evaluation
العنوان: | Salicylanilide Acetates: Synthesis and Antibacterial Evaluation |
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المؤلفون: | Jarmila Vinsova, Ales Imramovsky, Vladimir Buchta, Martina Ceckova, Martin Dolezal, Frantisek Staud, Josef Jampilek, Jarmila Kaustova |
المصدر: | Molecules, Vol 12, Iss 1, Pp 1-12 (2008) |
بيانات النشر: | MDPI AG, 2008. |
سنة النشر: | 2008 |
المجموعة: | LCC:Organic chemistry |
مصطلحات موضوعية: | Salicylanilide acetates, in vitro antifungal activity, in vitro antimycobacterial activity, lipophilicity determination, cytotoxicity, structure-activity relationships, Organic chemistry, QD241-441 |
الوصف: | A new series of salicylanilide acetates was synthesized and evaluated for their in vitro antifungal and antituberculotic activity. Some of the evaluated compounds possessed comparable or better antifungal activity than a fluconazole standard. All these compounds exhibited very good potential and their in vitro activity against drug resistant and sensitive clinical isolates of Mycobacteria were found to be equivalent or better than a standard of isoniazide, a well-known first-line drug for tuberculosis treatment. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1420-3049 36538914 |
Relation: | https://www.mdpi.com/1420-3049/12/1/1; https://doaj.org/toc/1420-3049 |
DOI: | 10.3390/12010001 |
URL الوصول: | https://doaj.org/article/ed46a365389149c8b7df0d87852a27ef |
رقم الأكسشن: | edsdoj.46a365389149c8b7df0d87852a27ef |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14203049 36538914 |
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DOI: | 10.3390/12010001 |