دورية أكاديمية
Mixed pathologies mimicking motor neuron disease: a case report and review of the literature
| العنوان: | Mixed pathologies mimicking motor neuron disease: a case report and review of the literature |
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| المؤلفون: | Avyarthana Dey, Ekhlas Assaedi, Wendy Johnston, Sanjay Kalra, Sumit Das |
| المصدر: | Folia Neuropathologica, Vol 59, Iss 4, Pp 403-408 (2021) |
| بيانات النشر: | Termedia Publishing House, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | amyotrophic lateral sclerosis, argyrophilic grain disease, cerebrovascular, alzheimer’s, neuropathology, overlap, Medicine |
| الوصف: | Amyotrophic lateral sclerosis (ALS) is classified as a motor neuron disease (MND) that can present with both upper and lower motor neuron signs. Concurrent ALS and frontotemporal dementia (FTD) is also a well-known phenomenon. Examples of other primary disorders mimicking ALS or ALS-FTD have been reported in the literature and recognition of these entities is important to ensure proper clinical management. We present here an unusual case of an 86-year-old male patient, clinically diagnosed with ALS and severe cognitive impairment thought to be due to FTD. Postmortem neuropathological examination of his brain and spinal cord did not reveal the typical findings of ALS or FTD. Rather, it revealed multiple non-ALS pathologies including argyrophilic grain disease (AGD), cerebrovascular disease, and Alzheimer’s type pathology. This case raises the possibility that mixed pathologies could mimic motor neuron disease. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1641-4640 1509-572X |
| Relation: | https://www.termedia.pl/Mixed-pathologies-mimicking-motor-neuron-disease-a-case-report-and-review-of-the-literature,20,45796,1,1.html; https://doaj.org/toc/1641-4640; https://doaj.org/toc/1509-572X |
| DOI: | 10.5114/fn.2021.111486 |
| URL الوصول: | https://doaj.org/article/51837b6a75ff4d73bffe1e87b89da5fe |
| رقم الأكسشن: | edsdoj.51837b6a75ff4d73bffe1e87b89da5fe |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16414640 1509572X |
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| DOI: | 10.5114/fn.2021.111486 |