دورية أكاديمية
Roles of Twist1 in lipid and glucose metabolism
| العنوان: | Roles of Twist1 in lipid and glucose metabolism |
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| المؤلفون: | Liuyifei Huang, Yan Xing, Xiaoxuan Ning, Zhixiang Yu, Xiao Bai, Limin Liu, Shiren Sun |
| المصدر: | Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-10 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Cytology |
| مصطلحات موضوعية: | Twist1, Lipid metabolism, Glucose metabolism, Adipose tissue, Fatty acid oxidation, Medicine, Cytology, QH573-671 |
| الوصف: | Abstract The abnormal lipid and glucose metabolisms are linked to the metabolic disorders, tumorigenesis, and fibrotic diseases, which attracts the increasing attention to find out the key molecules involved in the lipid and glucose metabolism as the possible therapeutic targets on these diseases. A transcriptional factor Twist1 has been associated with not only the embryonic development, cancer, and fibrotic diseases, but also the regulation of lipid and glucose metabolism. In this review, we will discuss the roles and mechanisms of Twist1 in the obesity-associated white adipose tissue inflammation and insulin resistance, brown adipose tissue metabolism, fatty acid oxidation, and glucose metabolism in skeletal muscle to provide a rational perspective to consider Twist1 as a potential treatment target in clinic. Video Abstract |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1478-811X |
| Relation: | https://doaj.org/toc/1478-811X |
| DOI: | 10.1186/s12964-023-01262-6 |
| URL الوصول: | https://doaj.org/article/53824e2a0af14cc88c85966c49c73c10 |
| رقم الأكسشن: | edsdoj.53824e2a0af14cc88c85966c49c73c10 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1478811X |
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| DOI: | 10.1186/s12964-023-01262-6 |