دورية أكاديمية
Favorable effect of corticosteroids in treating acute-on-chronic liver failure underlying chronic hepatitis B
| العنوان: | Favorable effect of corticosteroids in treating acute-on-chronic liver failure underlying chronic hepatitis B |
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| المؤلفون: | Hyeji Kim, Jung Hyun Kwon, Yong Hee Kim, Soon Woo Nam, Jong Yul Lee, Jeong Won Jang |
| المصدر: | Clinical and Molecular Hepatology, Vol 24, Iss 4, Pp 430-435 (2018) |
| بيانات النشر: | Korean Association for the Study of the Liver, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | acute-on-chronic liver failure, chronic hepatitis b, corticosteroid, exacerbation, reactivation, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Acute-on-chronic liver failure (ACLF) occurs in the presence of a chronic liver disease or cirrhosis, and often results from exacerbation of chronic hepatitis B (CHB). The efficacy of corticosteroid treatment in ACLF patients with underlying CHB remains unclear. We report the case of a 50-year-old woman who experienced ACLF due to CHB exacerbation and was treated with a combination of corticosteroids and nucleot(s)ide analogue (NUC). The patient showed rapid decompensation due to CHB exacerbation. Three months of antiviral therapy produced no improvement in liver function. Combination therapy with corticosteroids and NUC was started, which did result in improvement of liver function. This case shows that the combined therapy of corticosteroids and NUC can be effective in treating ACLF due to CHB exacerbation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2287-2728 2287-285X |
| Relation: | http://e-cmh.org/upload/pdf/cmh-2017-0016.pdf; https://doaj.org/toc/2287-2728; https://doaj.org/toc/2287-285X |
| DOI: | 10.3350/cmh.2017.0016 |
| URL الوصول: | https://doaj.org/article/d56cf86ce07e4595a6428c1c795e987b |
| رقم الأكسشن: | edsdoj.56cf86ce07e4595a6428c1c795e987b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22872728 2287285X |
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| DOI: | 10.3350/cmh.2017.0016 |