دورية أكاديمية
The Effect of Metformine on Glucose Control in Patients with Diabetes Type 1
| العنوان: | The Effect of Metformine on Glucose Control in Patients with Diabetes Type 1 |
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| المؤلفون: | Amir Ziaee, Navid Mohammadi, Homayoon Sheikholeslami, Zohreh Yazdi, Behrang Motamed |
| المصدر: | پزشکی بالینی ابن سینا, Vol 17, Iss 2, Pp 11-16 (2010) |
| بيانات النشر: | Hamadan University of Medical Sciences, 2010. |
| سنة النشر: | 2010 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | blood glucose, diabetes mellitus, type 1, insulin resistance, metformine, Medicine |
| الوصف: | Introduction & Objective: Metabolic control in adolescents with type 1 DM who are in pubertal period will be impaired, thus finding a therapeutic strategy such as adding metformin to insulin to reduce insulin resistance will be useful in blood glucose control and metabolic state improvement. Materials & Methods: This was a randomized double blind placebo controlled 3-month trial metformin therapy in 32 adolescents with type 1 DM. These patients were divided in two groups of metformin and placebo and treated with metformin and placebo for 3-months. Their HbA1C, FBS, Insulin dosage, TG, Cholesterol, and LDL were measured at the initiation and end of the treatment. Results: After the study there was a significant improvement of FBS and TG in metformin group versus placebo group (P=0.02 and P=0.028 in order). But, there was not significant difference in other variables such as BMI, insulin dosage, HbA1C, Cholesterol and LDL between the two groups. Conclusion: Metformin treatment in teenagers with type1 DM who are in pubertal period will improve the control of FBS and lowers TG but has not any significant effect on HbA1C, BMI, insulin dosage, Cholesterol and LDL. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Persian |
| تدمد: | 2588-722X 2588-7238 |
| Relation: | http://sjh.umsha.ac.ir/article-1-273-en.html; https://doaj.org/toc/2588-722X; https://doaj.org/toc/2588-7238 |
| URL الوصول: | https://doaj.org/article/57bb8cf44b6440c2bdce41446f2cc987 |
| رقم الأكسشن: | edsdoj.57bb8cf44b6440c2bdce41446f2cc987 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2588722X 25887238 |
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