دورية أكاديمية
Machine learning analysis of adrenal lesions: preliminary study evaluating texture analysis in the differentiation of adrenal lesions
| العنوان: | Machine learning analysis of adrenal lesions: preliminary study evaluating texture analysis in the differentiation of adrenal lesions |
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| المؤلفون: | Canan Altay, Işıl Başara Akın, Abdullah Hakan Özgül, Süleyman Cem Adıyaman, Abdullah Serkan Yener, Mustafa Seçil |
| المصدر: | Diagnostic and Interventional Radiology, Vol 29, Iss 2, Pp 234-243 (2023) |
| بيانات النشر: | Galenos Publishing House, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | adrenal adenoma, adrenal glands, adrenal mass, computed tomography, texture analysis, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | PURPOSEThis study aimed to determine the accuracy of texture analysis in differentiating adrenal lesions on unenhanced computed tomography (CT) images.METHODSIn this single-center retrospective study, 166 adrenal lesions in 140 patients (64 women, 76 men; mean age 56.58 ± 13.65 years) were evaluated between January 2015 and December 2019. The lesions consisted of 54 lipid-rich adrenal adenomas, 37 lipid-poor adrenal adenomas (LPAs), 56 adrenal metastases (ADM), and 19 adrenal pheochromocytomas (APhs). Each adrenal lesion was segmented by manually contouring the borders of the lesion on unenhanced CT images. A texture analysis of the CT images was performed using Local Image Feature Extraction software. First-order and second-order texture parameters were assessed, and 45 features were extracted from each lesion. One-Way analysis of variance with Bonferroni correction and the Mann–Whitney U test was performed to determine the relationships between the texture features and adrenal lesions. Receiver operating characteristic curves were performed for lesion discrimination based on the texture features. Logistic regression analysis was used to generate logistic models, including only the texture parameters with a high-class separation capacity (i.e., P < 0.050). SPSS software was used for all statistical analyses.RESULTSFirst-order and second-order texture parameters were identified as significant factors capable of differentiating among the four lesion types (P < 0.050). The logistic models were evaluated to ascertain the relationships between LPA and ADM, LPA and APh, and ADM and APh. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the first model (LPA vs. ADM) were 85.7%, 70.3%, 81.3%, 76.4%, and 79.5%, respectively. The sensitivity, specificity, PPV, NPV, and accuracy of the second model (LPA vs. APh) were all 100%. The sensitivity, specificity, PPV, NPV, and accuracy of the third model (ADM vs. APh) were 87.5%, 82%, 36.8%, 98.2%, and 82.7%, respectively.CONCLUSIONTexture features may help in the characterization of adrenal lesions on unenhanced CT images. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1305-3825 1305-3612 |
| Relation: | http://www.dirjournal.org/archives/archive-detail/article-preview/machine-learning-analysis-of-adrenal-lesions-preli/57236; https://doaj.org/toc/1305-3825; https://doaj.org/toc/1305-3612 |
| DOI: | 10.5152/dir.2022.21266 |
| URL الوصول: | https://doaj.org/article/57c0ef507e7f465384b3a9b8c49cbbbc |
| رقم الأكسشن: | edsdoj.57c0ef507e7f465384b3a9b8c49cbbbc |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13053825 13053612 |
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| DOI: | 10.5152/dir.2022.21266 |