دورية أكاديمية
Genetic Parameter Estimation and Genome-Wide Association Analysis of Social Genetic Effects on Average Daily Gain in Purebreds and Crossbreds
العنوان: | Genetic Parameter Estimation and Genome-Wide Association Analysis of Social Genetic Effects on Average Daily Gain in Purebreds and Crossbreds |
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المؤلفون: | Ha-Seung Seong, Young-Sin Kim, Soo-Jin Sa, Yongdae Jeong, Joon-Ki Hong, Eun-Seok Cho |
المصدر: | Animals, Vol 12, Iss 17, p 2300 (2022) |
بيانات النشر: | MDPI AG, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Veterinary medicine LCC:Zoology |
مصطلحات موضوعية: | social genetic effect, average daily gain, purebred, crossbred, Veterinary medicine, SF600-1100, Zoology, QL1-991 |
الوصف: | Average daily gain (ADG) is an important growth trait in the pig industry. The direct genetic effect (DGE) has been studied mainly to assess the association between genetic information and economic traits. The social genetic effect (SGE) has been shown to affect ADG simultaneously with the DGE because of group housing systems. We conducted this study to elucidate the genetic characteristics and relationships of the DGE and SGE of purebred Korean Duroc and crossbred pigs by single-step genomic best linear unbiased prediction and a genome-wide association study. We used the genotype, phenotype, and pedigree data of 1779, 6022, and 7904 animals, respectively. Total heritabilities on ADG were 0.19 ± 0.04 and 0.39 ± 0.08 for purebred and crossbred pigs, respectively. The genetic correlation was the greatest (0.77 ± 0.12) between the SGE of purebred and DGE of crossbred pigs. We found candidate genes located in the quantitative trait loci (QTLs) for the SGE that were associated with behavior and neurodegenerative diseases, and candidate genes in the QTLs for DGE that were related to body mass, size of muscle fiber, and muscle hypertrophy. These results suggest that the genomic selection of purebred animals could be applied for crossbred performance. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2076-2615 |
Relation: | https://www.mdpi.com/2076-2615/12/17/2300; https://doaj.org/toc/2076-2615 |
DOI: | 10.3390/ani12172300 |
URL الوصول: | https://doaj.org/article/58fc233de0ed449499370803fe8aca6b |
رقم الأكسشن: | edsdoj.58fc233de0ed449499370803fe8aca6b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20762615 |
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DOI: | 10.3390/ani12172300 |