دورية أكاديمية
Epigenetics of Hypogonadotropic Hypogonadism: Molecular Mimicry between Severe Acute Respiratory Syndrome Coronavirus 2 and KISSR
| العنوان: | Epigenetics of Hypogonadotropic Hypogonadism: Molecular Mimicry between Severe Acute Respiratory Syndrome Coronavirus 2 and KISSR |
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| المؤلفون: | Darja Kanduc |
| المصدر: | Global Medical Genetics, Vol 10, Iss 02, Pp 129-132 (2023) |
| بيانات النشر: | Georg Thieme Verlag KG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Genetics LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | kissr, sars-cov-2, autoimmunity: hypogonadotropic hypogonadism, Genetics, QH426-470, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | This study analyzed KISS1 and its receptor KISSR for peptide sharing with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was found that SARS-CoV-2 shares numerous minimal immune pentapeptide determinants with KISSR only. The peptide sharing has a high immunologic potential since almost all the common peptides are present in 101 SARS-CoV-2-derived immunoreactive epitopes. Data are in favor of configuring molecular mimicry as an epigenetic factor that can alter KISSR thus causing the hypogonadotropic hypogonadism syndrome with which altered KISSR associates. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2699-9404 |
| Relation: | https://doaj.org/toc/2699-9404 |
| DOI: | 10.1055/s-0043-1770767 |
| URL الوصول: | https://doaj.org/article/5903c4275a2e4638922d56495c75a565 |
| رقم الأكسشن: | edsdoj.5903c4275a2e4638922d56495c75a565 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26999404 |
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| DOI: | 10.1055/s-0043-1770767 |