دورية أكاديمية

Sedation with a 1:1 mixture of etomidate and propofol for gastroscopy in hypertensive elderly patients

التفاصيل البيبلوغرافية
العنوان: Sedation with a 1:1 mixture of etomidate and propofol for gastroscopy in hypertensive elderly patients
المؤلفون: Yanpeng Liu, Yiping Huang, Ruoguo Wang, Yongji Zhai, Kechang Huang, Zhanjie Ren
المصدر: The Journal of Clinical Hypertension, Vol 25, Iss 8, Pp 778-783 (2023)
بيانات النشر: Wiley, 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: elderly, etomidate, gastroscopy, hypertension, propofol, sedation, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Abstract We hypothesized that the combined use of etomidate and propofol for endoscopic sedation in elderly hypertensive patients could reduce adverse reactions while providing ideal sedation. To validate our hypothesis, we conducted a prospective, randomized, controlled, double‐blinded study. A total of 360 elderly hypertensive patients scheduled for gastroscopy at our hospital were enrolled in the study, of whom 328 completed the trial. The patients were randomly assigned to one of three groups: the propofol group (group P), the etomidate group (group E), or the propofol‐etomidate combination group (mixed at a ratio of 1:1, group PE). We collected and analyzed the cardiopulmonary effects and side effects in each group. Regardless of the sedation drug used, the systolic blood pressure, mean blood pressure, and heart rate of involved patients were significantly affected. Oxygen desaturation and injection pain were more common in group P compared to groups E (33.6% vs. 14.8%, 31.8% vs. 2.7%, both P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1751-7176
1524-6175
Relation: https://doaj.org/toc/1524-6175; https://doaj.org/toc/1751-7176
DOI: 10.1111/jch.14693
URL الوصول: https://doaj.org/article/5ac157ac595543b3baab61d47a18eec0
رقم الأكسشن: edsdoj.5ac157ac595543b3baab61d47a18eec0
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17517176
15246175
DOI:10.1111/jch.14693