دورية أكاديمية
Sedation with a 1:1 mixture of etomidate and propofol for gastroscopy in hypertensive elderly patients
العنوان: | Sedation with a 1:1 mixture of etomidate and propofol for gastroscopy in hypertensive elderly patients |
---|---|
المؤلفون: | Yanpeng Liu, Yiping Huang, Ruoguo Wang, Yongji Zhai, Kechang Huang, Zhanjie Ren |
المصدر: | The Journal of Clinical Hypertension, Vol 25, Iss 8, Pp 778-783 (2023) |
بيانات النشر: | Wiley, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | elderly, etomidate, gastroscopy, hypertension, propofol, sedation, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Abstract We hypothesized that the combined use of etomidate and propofol for endoscopic sedation in elderly hypertensive patients could reduce adverse reactions while providing ideal sedation. To validate our hypothesis, we conducted a prospective, randomized, controlled, double‐blinded study. A total of 360 elderly hypertensive patients scheduled for gastroscopy at our hospital were enrolled in the study, of whom 328 completed the trial. The patients were randomly assigned to one of three groups: the propofol group (group P), the etomidate group (group E), or the propofol‐etomidate combination group (mixed at a ratio of 1:1, group PE). We collected and analyzed the cardiopulmonary effects and side effects in each group. Regardless of the sedation drug used, the systolic blood pressure, mean blood pressure, and heart rate of involved patients were significantly affected. Oxygen desaturation and injection pain were more common in group P compared to groups E (33.6% vs. 14.8%, 31.8% vs. 2.7%, both P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1751-7176 1524-6175 |
Relation: | https://doaj.org/toc/1524-6175; https://doaj.org/toc/1751-7176 |
DOI: | 10.1111/jch.14693 |
URL الوصول: | https://doaj.org/article/5ac157ac595543b3baab61d47a18eec0 |
رقم الأكسشن: | edsdoj.5ac157ac595543b3baab61d47a18eec0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17517176 15246175 |
---|---|
DOI: | 10.1111/jch.14693 |