دورية أكاديمية
P6.11 RELATIONSHIPS BETWEEN ENDOTHELIAL FUNCTION, ARTERIAL ELASTICITY AND BAROREFLEX SENSITIVITY
| العنوان: | P6.11 RELATIONSHIPS BETWEEN ENDOTHELIAL FUNCTION, ARTERIAL ELASTICITY AND BAROREFLEX SENSITIVITY |
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| المؤلفون: | A. Pinter, T. Horvath, D. Cseh, M. Kollai |
| المصدر: | Artery Research, Vol 3, Iss 4 (2009) |
| بيانات النشر: | BMC, 2009. |
| سنة النشر: | 2009 |
| المجموعة: | LCC:Specialties of internal medicine LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Endothelium derived nitric oxide (NO) increases conduit artery distensibility, through relaxation of vascular smooth muscle. Barosensory wall distensibility influences the mechanical component of baroreflex sensitivity (BRS) by modifying the baroreceptor stimulus. NO bioavailability may also affect the neural component of BRS, by influencing afferent sensitivity, central neural processing or neuroeffector mechanisms. We aimed to study the relationships between the above variables in young healthy volunteers (n=28, male:female 10:18; age 16.5±1.4 years). To this end we measured brachial artery endothelial function by brachial flow mediated dilatation normalized with peak mean shear rates (nFMD) and carotid artery biomechanical parameters and blood pressure by ultrasonographic wall-tracking and tonometry. From these variables elastic parameters were calculated. BRS was measured by the spontaneous sequence method (Seq+). The mean values (mean±SD) were 5.41±1.49 [10−3/mmHg] and 4.79±1.14 for carotid artery distensibility coefficient and stiffness index β, respectively, 2.59±1.00 for nFMD and 25±16 [ms/mmHg] for Seq+. Using correlation and linear regression analysis, we found that elastic parameters were not related, but BRS was significantly related to nFMD (r=0.486, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1876-4401 |
| Relation: | https://www.atlantis-press.com/article/125927338/view; https://doaj.org/toc/1876-4401 |
| DOI: | 10.1016/j.artres.2009.10.078 |
| URL الوصول: | https://doaj.org/article/5af7c694ff51456a93a18ec44691339f |
| رقم الأكسشن: | edsdoj.5af7c694ff51456a93a18ec44691339f |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 18764401 |
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| DOI: | 10.1016/j.artres.2009.10.078 |