دورية أكاديمية
Produção e caracterização de anticorpos monoclonais contra toxina épsilon de Clostridium perfringens Tipo D Production and characterization of monoclonal antibodies against Clostridium perfringens Type D epsilon toxin
| العنوان: | Produção e caracterização de anticorpos monoclonais contra toxina épsilon de Clostridium perfringens Tipo D Production and characterization of monoclonal antibodies against Clostridium perfringens Type D epsilon toxin |
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| المؤلفون: | Theonys Diógenes Freitas, Luis Guilherme Dias Heneine, Felipe Masiero Salvarani, Rodrigo Otávio Silveira Silva, Catarina Guimarães Rocha Dourado Lima, Prhiscylla Sadanã Pires, Ronnie Antunes de Assis, Francisco Carlos Faria Lobato |
| المصدر: | Ciência Rural, Vol 39, Iss 1, Pp 269-271 (2009) |
| بيانات النشر: | Universidade Federal de Santa Maria, 2009. |
| سنة النشر: | 2009 |
| المجموعة: | LCC:Agriculture LCC:Agriculture (General) |
| مصطلحات موضوعية: | Clostridium perfringens, toxina épsilon, anticorpos monoclonais, epsilon toxin, monoclonal antibodies, Agriculture, Agriculture (General), S1-972 |
| الوصف: | Clostridium perfringens tipo D é o agente etiológico da enterotoxemia em ruminantes, causada pela toxina épsilon e caracterizada por edema cardíaco, pulmonar, renal e cerebral. Anticorpos monoclonais contra toxina épsilon de C. perfringens tipo D foram produzidos a partir da fusão da linhagen de mieloma P3-X63-Ag8 653 com células do baço de camundongos Balb/c imunizados com o toxóide épsilon. Seis linhagens de híbridos secretores de anticorpos monoclonais das classes e IgM e IgG foram estabelecidas.Clostridium perfringens type D is the aetiological agent of enterotoxemia in ruminants. The disease is caused by epsilon toxin characterized by cardiac, pulmonary, kidney and brain edema. Monoclonal antibodies were produced by using myeloma cell line P3-X63-Ag8 653 fused with spleen cells from Balb/c mice, immunized with epsilon toxoid of C. perfringens type D. Six hybrids were established secreting monoclonal antibodies of the IgM class and IgG3 subclass. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 0103-8478 1678-4596 35231432 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000100046; https://doaj.org/toc/0103-8478; https://doaj.org/toc/1678-4596 |
| URL الوصول: | https://doaj.org/article/5dd3523143234ed8a2dce46d49708bb5 |
| رقم الأكسشن: | edsdoj.5dd3523143234ed8a2dce46d49708bb5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 01038478 16784596 35231432 |
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