دورية أكاديمية
Peripartum outcomes and immune responses after SARS-CoV-2 infection in the third trimester of pregnancy
العنوان: | Peripartum outcomes and immune responses after SARS-CoV-2 infection in the third trimester of pregnancy |
---|---|
المؤلفون: | Qi Shen, Shuai Dong, Neelam Kumari Shah, Yuan Liang, Jie Wang, Yan-Hong Shan, Jin He |
المصدر: | BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-11 (2024) |
بيانات النشر: | BMC, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Gynecology and obstetrics |
مصطلحات موضوعية: | COVID-19, Pregnancy, Peripartum outcomes, Immune response, Gynecology and obstetrics, RG1-991 |
الوصف: | Abstract Background SARS-CoV-2 infection in pregnant women during the third trimester resulted in overall adverse pregnancy outcomes compared to non-infected controls and a unique humoral and cellular response at delivery. In this study we aimed to assess the impact of SARS-CoV-2 infection on maternal/neonatal peripartum outcomes andimmunological profiles. Method In this study, we recruited 304 SARS-CoV-2 infected pregnant women and 910 SARS-CoV-2 non-infected pregnant women who were admitted for delivery. Peripartum and neonates’ outcomes response to SARS-CoV-2 infection were analyzed. Furthermore, we characterized the antibody and cytokines profile in SARS-CoV-2 infected maternal blood (MB) and cord blood (CB). We also assessed routine laboratory tests and liver function tests in MB before labor. Unpaired T test, Mann-Whitney test and Spearman test were used to analyze the data. Results SARS-CoV-2 infected pregnant women were significantly associated with increased risk of adverse pregnancy outcomes, including preterm labor (13.8% vs. 9.5%, p = 0.033) and meconium-stained amniotic fluid (8.9% vs. 5.5%, p = 0.039). The risk of low birth weight ( |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1471-2393 |
Relation: | https://doaj.org/toc/1471-2393 |
DOI: | 10.1186/s12884-024-06707-5 |
URL الوصول: | https://doaj.org/article/625738cd5d814e9a8b8435575a5e012f |
رقم الأكسشن: | edsdoj.625738cd5d814e9a8b8435575a5e012f |
قاعدة البيانات: | Directory of Open Access Journals |
كن أول من يترك تعليقا!