دورية أكاديمية
Heat shock protein 70 level of synovial fluid in rheumatoid arthritis versus osteoarthritis: a comparative study
| العنوان: | Heat shock protein 70 level of synovial fluid in rheumatoid arthritis versus osteoarthritis: a comparative study |
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| المؤلفون: | Gharibdoost F, Samadi F, Taghipoor R, Akbarian M, Shahram F, Nadji A, Jamshidi A R, Davatchi F |
| المصدر: | Tehran University Medical Journal, Vol 65, Iss 7, Pp 28-31 (2007) |
| بيانات النشر: | Tehran University of Medical Sciences, 2007. |
| سنة النشر: | 2007 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | Osteoarthritis, heat shock protein 70, Medicine (General), R5-920 |
| الوصف: | Background: Heat-shock proteins are part of a strictly controlled biological system that allows organisms to respond to environmental stresses. Different proinflammatory cytokines are present in the synovial tissue of rheumatoid arthritis patients. Such tissues respond to stress and induce heat-shock proteins. In addition, synovial cells are exposed to mechanical stress caused by joint motion. The effects of mechanical stress on the metabolism of the synovial cells may be substantial, even pathogenic. Heat-shock proteins are often implicated in the pathogenesis of rheumatoid arthritis. Here, we compare the levels of heat-shock protein 70 from the synovial fluid of rheumatoid arthritis and osteoarthritis patients.Methods: Synovial fluid samples from 34 rheumatoid arthritis patients and 34 osteoar-thritis patients were analyzed for heat-shock protein 70 by an ELISA method. Statistical analysis was performed using independent T-test and one-way ANOVA. Differences were considered statistically significant at p< 0.05.Results: The mean value of synovial fluid heat-shock protein 70 levels in rheumatoid arthritis patients was 156.30 ±128.51 and that of osteoarthritis patients was 14.98 ±11.58. The differences were statistically significant at p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Persian |
| تدمد: | 1683-1764 1735-7322 |
| Relation: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/3926.pdf&manuscript_id=3926; https://doaj.org/toc/1683-1764; https://doaj.org/toc/1735-7322 |
| URL الوصول: | https://doaj.org/article/67b2f3ccf77244dcab91f7278d635adf |
| رقم الأكسشن: | edsdoj.67b2f3ccf77244dcab91f7278d635adf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16831764 17357322 |
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