دورية أكاديمية
Surgery versus radiofrequency ablation in patients with Child- Pugh class-A/single small (≤3 cm) hepatocellular carcinoma
| العنوان: | Surgery versus radiofrequency ablation in patients with Child- Pugh class-A/single small (≤3 cm) hepatocellular carcinoma |
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| المؤلفون: | Jungnam Lee, Young-Joo Jin, Seung Kak Shin, Jung Hyun Kwon, Sang Gyune Kim, Young Ju Suh, Yujin Jeong, Jung Hwan Yu, Jin-Woo Lee, Oh Sang Kwon, Soon Woo Nahm, Young Seok Kim |
| المصدر: | Clinical and Molecular Hepatology, Vol 28, Iss 2, Pp 207-218 (2022) |
| بيانات النشر: | Korean Association for the Study of the Liver, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | hepatocellular carcinoma, operation, radiofrequency ablation, survival, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background/Aims We compared the post-treatment overall survival (OS) and recurrence-free survival (RFS) between patients with Child-Turcotte-Pugh (CTP) class-A and single small (≤3 cm) hepatocellular carcinoma (HCC) treated by surgical resection (SR) and radiofrequency ablation (RFA). Methods We retrospectively analyzed 391 HCC patients with CTP class-A who underwent SR (n=232) or RFA (n=159) as first-line therapy for single small (≤3 cm) HCC. Survival was compared according to the tumor size (≤2 cm/2–3 cm) and the presence of cirrhosis. Inverse probability of treatment weighting (IPW) method was used to estimate the average causal effect of treatment. Results The median follow-up period was 64.8 months (interquartile range, 0.1–162.6). After IPW, the estimated OS was similar in the SR and RFA groups (P=0.215), and even in patients with HCC of ≤2 cm (P=0.816) and without cirrhosis (P=0.195). The estimated RFS was better in the SR group than in the RFA groups (P=0.005), also in patients without cirrhosis (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2287-2728 2287-285X |
| Relation: | http://e-cmh.org/upload/pdf/cmh-2021-0294.pdf; https://doaj.org/toc/2287-2728; https://doaj.org/toc/2287-285X |
| DOI: | 10.3350/cmh.2021.0294 |
| URL الوصول: | https://doaj.org/article/68e9de90b19d41c7b688ff09e7f3a6d8 |
| رقم الأكسشن: | edsdoj.68e9de90b19d41c7b688ff09e7f3a6d8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22872728 2287285X |
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| DOI: | 10.3350/cmh.2021.0294 |