دورية أكاديمية
Molecular typing of antibiotic-resistant Staphylococcus aureus in Nigeria
| العنوان: | Molecular typing of antibiotic-resistant Staphylococcus aureus in Nigeria |
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| المؤلفون: | S.M. O’Malley, F.E. Emele, F.O. Nwaokorie, N. Idika, A.K. Umeizudike, I. Emeka-Nwabunnia, B.M. Hanson, R. Nair, S.E. Wardyn, T.C. Smith |
| المصدر: | Journal of Infection and Public Health, Vol 8, Iss 2, Pp 187-193 (2015) |
| بيانات النشر: | Elsevier, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Infectious and parasitic diseases LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270 |
| الوصف: | Summary: Background: Antibiotic-resistant Staphylococcus aureus including methicillin-resistant strains (MRSA) are a major concern in densely populated urban areas. Initial studies of S. aureus in Nigeria indicated existence of antibiotic-resistant S. aureus strains in clinical and community settings. Methods: 73 biological samples (40 throat, 23 nasal, 10 wound) were collected from patients and healthcare workers in three populations in Nigeria: Lagos University Teaching Hospital, Nigerian Institute of Medical Research, and Owerri General Hospital. Results: S. aureus was isolated from 38 of 73 samples (52%). Of the 38 S. aureus samples, 9 (24%) carried the Panton-Valentine leukocidin gene (PVL) while 16 (42%) possessed methicillin resistance genes (mecA). Antibiotic susceptibility profiles indicated resistance to several broad-spectrum antibiotics. Conclusion: Antibiotic-resistant S. aureus isolates were recovered from clinical and community settings in Nigeria. Insight about S. aureus in Nigeria may be used to improve antibiotic prescription methods and minimize the spread of antibiotic-resistant organisms in highly populated urban communities similar to Lagos, Nigeria. Keywords: Antibiotic resistance, Staphylococcus aureus, Nigeria, Epidemiology, spa typing, PVL, mecA |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1876-0341 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1876034114001397; https://doaj.org/toc/1876-0341 |
| DOI: | 10.1016/j.jiph.2014.08.001 |
| URL الوصول: | https://doaj.org/article/6a631f8d27224623affa67306c751b93 |
| رقم الأكسشن: | edsdoj.6a631f8d27224623affa67306c751b93 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 18760341 |
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| DOI: | 10.1016/j.jiph.2014.08.001 |