دورية أكاديمية

Effects of mouse nerve growth factor in treating cerebral injury in acute period caused by cerebral hemorrhage

التفاصيل البيبلوغرافية
العنوان: Effects of mouse nerve growth factor in treating cerebral injury in acute period caused by cerebral hemorrhage
المؤلفون: Yang Sun, Xiaobo Zhu, Junling Hou, Kun Hou, Weiwei Jin
المصدر: Saudi Journal of Biological Sciences, Vol 27, Iss 10, Pp 2701-2705 (2020)
بيانات النشر: Elsevier, 2020.
سنة النشر: 2020
المجموعة: LCC:Biology (General)
مصطلحات موضوعية: NGF, Cerebral hemorrhage, BNP, NF-kB, Biology (General), QH301-705.5
الوصف: Objective: To explore the clinical effects of mouse Nerve Growth Factor (NGF) in treating cerebral injury in acute period caused by cerebral hemorrhage, observe its influences on Natriuretic Peptide (BNP) and NF-kB Level and evaluate its safety and efficiency. Methods: 96 cases with acute cerebral hemorrhage from January 2016 to January 2017 in our hospital were recruited as this study, they were randomly divided into the control group and the observation group, each 48 cases. The observation group were given NGF on the treatment of the control group. NIHSS, BI score, adverse reactions records were compared in two groups before and after treatment. The clinical effective rate were evaluated. Then BNP and NF-KB Level of patients in two groups before and after treatment were detected by using ELISA. Results: There were no significant differences in two groups before treatment with respect to NIHSS and BI score (P > 0.05). After treatment, NIHSS score in the observation group significantly lower than the control group. BI score in the observation group significantly higher than the control group, differences had obvious significance (P 0.05). BNP and NF-kB Level decreased with different levels in two groups after treatment, and the observation group lower than the control group at the same time (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1319-562X
Relation: http://www.sciencedirect.com/science/article/pii/S1319562X20302564; https://doaj.org/toc/1319-562X
DOI: 10.1016/j.sjbs.2020.06.017
URL الوصول: https://doaj.org/article/ece6ca49217543478910976fb2ce3813
رقم الأكسشن: edsdoj.6ca49217543478910976fb2ce3813
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1319562X
DOI:10.1016/j.sjbs.2020.06.017