دورية أكاديمية
Narrow-band imaging with magnifying endoscopy for Peyer's patches is useful in predicting the recurrence of remissive patients with ulcerative colitis
| العنوان: | Narrow-band imaging with magnifying endoscopy for Peyer's patches is useful in predicting the recurrence of remissive patients with ulcerative colitis |
|---|---|
| المؤلفون: | Satoshi Hiyama, Hideki Iijima, Syoichiro Kawai, Akira Mukai, Eri Shiraishi, Shuko Iwatani, Toshio Yamaguchi, Manabu Araki, Yoshito Hayashi, Shinichiro Shinzaki, Tsunekazu Mizushima, Masahiko Tsujii, Tetsuo Takehara |
| المصدر: | Intestinal Research, Vol 14, Iss 4, Pp 314-321 (2016) |
| بيانات النشر: | Korean Association for the Study of Intestinal Diseases, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Medicine LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Colitis, ulcerative, Peyer's patch, Narrow-band imaging, Medicine, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background/AimsPeyer's patches (PPs) are aggregates of lymphoid follicles that are mainly located in the distal ileum; they play a major role in mucosal immunity. We recently reported that patients with ulcerative colitis (UC) have alterations in PPs that can be detected using narrow-band imaging with magnifying endoscopy (NBI-ME). However, the usefulness of NBI-ME in UC treatment as a whole is still unknown.MethodsWe collected NBI-ME images of PPs from 67 UC patients who had undergone ileocolonoscopy. We evaluated changes in the villi using the "villi index," which is based on three categories: irregular formation, hyperemia, and altered vascular network pattern. The patients were divided into two groups on the basis of villi index: low (L)- and high (H)-types. We then determined the correlation between morphological alteration of the PPs and various clinical characteristics. In 52 patients who were in clinical remission, we also analyzed the correlation between NBI-ME findings of PPs and clinical recurrence.ResultsThe time to clinical recurrence was significantly shorter in remissive UC patients with H-type PPs than in those with L-type PPs (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1598-9100 2288-1956 |
| Relation: | http://www.irjournal.org/upload/pdf/ir-14-314.pdf; https://doaj.org/toc/1598-9100; https://doaj.org/toc/2288-1956 |
| DOI: | 10.5217/ir.2016.14.4.314 |
| URL الوصول: | https://doaj.org/article/72c49d105ece42cf9bb637c15a849330 |
| رقم الأكسشن: | edsdoj.72c49d105ece42cf9bb637c15a849330 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15989100 22881956 |
|---|---|
| DOI: | 10.5217/ir.2016.14.4.314 |