دورية أكاديمية
Carcinosarcoma of Breast with Hormone Receptor and Her2/neu Positivity
العنوان: | Carcinosarcoma of Breast with Hormone Receptor and Her2/neu Positivity |
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المؤلفون: | Deepti Agarwal, Vijay Malik, Ruchi Agarwa, M.K. Garg, Shilpa Garg |
المصدر: | National Journal of Laboratory Medicine, Vol 5, Iss 1, Pp 26-29 (2016) |
بيانات النشر: | JCDR Research and Publications Pvt. Ltd., 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Microbiology LCC:Chemistry |
مصطلحات موضوعية: | anti-cytokeratin, metaplastic breast carcinomas (mbc), vimentin, Microbiology, QR1-502, Chemistry, QD1-999 |
الوصف: | Carcinosarcoma is an extremely rare tumor of the breast comprising of two distinct cell lines i.e. the epithelial and mesenchymal. It is a highly aggressive tumor with a poor prognosis compared to other breast cancers with a reported incidence of less than 1% of all the breast cancers. A 35 year old female presented to surgical outpatient with a fungating mass in the right breast where cytological analysis from the affected areas revealed spindle cells of malignant potential. A modified radical mastectomy was performed and following histopathological examination of the excised tissue, a final diagnosis of carcinosarcoma of breast was concluded. Immunological staining done showed a negative staining for PR and positive staining for ER, Her-2/neu and CK receptors, as against the conventional triple negative staining pattern. Along with a rare staining pattern of this rare tumor reported in literature, this case merits presentation owing to its diagnostic and therapeutic challenges. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2277-8551 2455-6882 |
Relation: | http://www.njlm.net/articles/PDF/2092/7-13279_F(AK)_PF1(VSUAK)_PFA(AK)_PF2(PVSU).pdf; https://doaj.org/toc/2277-8551; https://doaj.org/toc/2455-6882 |
DOI: | 10.7860/NJLM/2016/13279:2092 |
URL الوصول: | https://doaj.org/article/d735a8962fdb47ccb3cd9eb5b162ed2c |
رقم الأكسشن: | edsdoj.735a8962fdb47ccb3cd9eb5b162ed2c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22778551 24556882 |
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DOI: | 10.7860/NJLM/2016/13279:2092 |