دورية أكاديمية
Heparin anticoagulation versus regional citrate anticoagulation for membrane therapeutic plasma exchange in patients with increased bleeding risk
العنوان: | Heparin anticoagulation versus regional citrate anticoagulation for membrane therapeutic plasma exchange in patients with increased bleeding risk |
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المؤلفون: | Jing Jiao, Yan Yu, Suijiao Wei, Xiujuan Tian, Xiaoxia Yang, Shidong Feng, Yajuan Li, Shiren Sun, Peng Zhang, Ming Bai |
المصدر: | Renal Failure, Vol 45, Iss 1 (2023) |
بيانات النشر: | Taylor & Francis Group, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Diseases of the genitourinary system. Urology |
مصطلحات موضوعية: | Membrane therapeutic plasma exchange, increased bleeding risk, regional citrate anticoagulation, heparin anticoagulation, Diseases of the genitourinary system. Urology, RC870-923 |
الوصف: | AbstractBackground Heparin anticoagulation (HA) is commonly employed for membrane therapeutic plasma exchange (mTPE). However, for patients with increased bleeding risk, there were controversial opinions on the use of HA versus regional citrate anticoagulation (RCA) for mTPE. Our present study aimed to evaluate the efficacy and safety of HA vs. RCA for mTPE in patients with increased bleeding risk.Methods Patients with increased bleeding risk who underwent mTPE between 2014 and 2021 in our center were screened. Observations of anticoagulation efficacy and safety were used as the study endpoints.Results A total of 108 patients with 368 mTPE sessions were included. Of the included patients, 38 and 70 received HA and RCA mTPE, respectively. There was no significant difference in the clotting of extracorporeal circuits between the HA and RCA groups (4.1% vs. 4.4%, p = 0.605). More bleeding episodes were observed in the HA group compared to the RCA group (16.4% vs. 4.4% mTPE sessions, p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0886022X 1525-6049 0886-022X |
Relation: | https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049 |
DOI: | 10.1080/0886022X.2023.2210691 |
URL الوصول: | https://doaj.org/article/76ec6ff0cf814836848c159d280527fd |
رقم الأكسشن: | edsdoj.76ec6ff0cf814836848c159d280527fd |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 0886022X 15256049 |
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DOI: | 10.1080/0886022X.2023.2210691 |