دورية أكاديمية
MRI-based diagnostic biomarkers for early onset pediatric multiple sclerosis
العنوان: | MRI-based diagnostic biomarkers for early onset pediatric multiple sclerosis |
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المؤلفون: | Martin Weygandt, Hannah-Maria Hummel, Katharina Schregel, Kerstin Ritter, Carsten Allefeld, Esther Dommes, Peter Huppke, JohnDylan Haynes, Jens Wuerfel, Jutta Gärtner |
المصدر: | NeuroImage: Clinical, Vol 7, Iss C, Pp 400-408 (2015) |
بيانات النشر: | Elsevier, 2015. |
سنة النشر: | 2015 |
المجموعة: | LCC:Computer applications to medicine. Medical informatics LCC:Neurology. Diseases of the nervous system |
مصطلحات موضوعية: | Pediatric multiple sclerosis, Early onset pediatric multiple sclerosis, Biomarkers, Diagnostic information, Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429 |
الوصف: | Currently, it is unclear whether pediatric multiple sclerosis (PMS) is a pathoetiologically homogeneous disease phenotype due to clinical and epidemiological differences between early and late onset PMS (EOPMS and LOPMS). Consequently, the question was raised whether diagnostic guidelines need to be complemented by specific EOPMS markers. To search for such markers, we analyzed cerebral MRI images acquired with standard protocols using computer-based classification techniques. Specifically, we applied classification algorithms to gray (GM) and white matter (WM) tissue probability parameters of small brain regions derived from T2-weighted MRI images of EOPMS patients (onset |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2213-1582 |
Relation: | http://www.sciencedirect.com/science/article/pii/S221315821400093X; https://doaj.org/toc/2213-1582 |
DOI: | 10.1016/j.nicl.2014.06.015 |
URL الوصول: | https://doaj.org/article/7794342c9002425480463222664cd197 |
رقم الأكسشن: | edsdoj.7794342c9002425480463222664cd197 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22131582 |
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DOI: | 10.1016/j.nicl.2014.06.015 |