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Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system

التفاصيل البيبلوغرافية
العنوان: Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system
المؤلفون: Yue Zhang, Fanhong Zeng, Xu Han, Jun Weng, Yi Gao
المصدر: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine (General)
LCC:Biochemistry
مصطلحات موضوعية: Lineage tracing, Gene targeting, Liver regeneration, Hepatic progenitor cells, Liver disease, The hepatitis B virus, Medicine (General), R5-920, Biochemistry, QD415-436
الوصف: Abstract Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue injury repairing, and tumor progression by tracing the fates of individual cells. Recently, lineage tracing has expanded the platforms available for disease model establishment, drug screening, cell plasticity research, and personalized medicine development in a molecular and cellular biology perspective. Lineage tracing provides new views for exploring digestive organ development and regeneration and techniques for digestive disease causes and progression. This review focuses on the lineage tracing technology and its application in digestive diseases.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1757-6512
Relation: http://link.springer.com/article/10.1186/s13287-020-01941-y; https://doaj.org/toc/1757-6512
DOI: 10.1186/s13287-020-01941-y
URL الوصول: https://doaj.org/article/78bd92a12f6a43f9a98e381581efda84
رقم الأكسشن: edsdoj.78bd92a12f6a43f9a98e381581efda84
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17576512
DOI:10.1186/s13287-020-01941-y