دورية أكاديمية
Cytosolic Distribution of Metals (Cd, Cu) and Metalloids (As, Se) in Livers and Gonads of Field-Collected Fish Exposed to an Environmental Contamination Gradient: An SEC-ICP-MS Analysis
| العنوان: | Cytosolic Distribution of Metals (Cd, Cu) and Metalloids (As, Se) in Livers and Gonads of Field-Collected Fish Exposed to an Environmental Contamination Gradient: An SEC-ICP-MS Analysis |
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| المؤلفون: | Nastassia Urien, Sabrina Jacob, Patrice Couture, Peter G. C. Campbell |
| المصدر: | Environments, Vol 5, Iss 9, p 102 (2018) |
| بيانات النشر: | MDPI AG, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Environmental technology. Sanitary engineering |
| مصطلحات موضوعية: | subcellular distribution, metal trafficking, metal detoxification, metal regulation, wild fish, contamination gradient, cytosolic biomolecules, size-exclusion high-performance liquid chromatography (HPLC), metallothionein, metallomics, Environmental technology. Sanitary engineering, TD1-1066 |
| الوصف: | The distribution of As, Cd, Cu and Se among biomolecules of different molecular weight (MW) in the heat-treated cytosolic fraction of livers and gonads of white suckers (WS; Catostomus commersonii) collected in a reference lake and in a lake subject to multi-metal contamination was investigated. Distribution profiles were obtained by separation of the heat-stable protein and peptide (HSP) fractions using size-exclusion high performance-liquid chromatography, coupled online to an inductively coupled plasma mass spectrometer, to quantify the associated metals. Metal-handling strategies did not vary between the reference and exposed fish, with the exception of As. Cadmium and Cu appeared associated with the heat-stable peptides metallothioneins (MTs), indicating their reasonable detoxification and regulation in WS. In contrast, Se and As were not bound to MTs, but rather, to biomolecules of lower MW ( |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-3298 |
| Relation: | http://www.mdpi.com/2076-3298/5/9/102; https://doaj.org/toc/2076-3298 |
| DOI: | 10.3390/environments5090102 |
| URL الوصول: | https://doaj.org/article/78de457c49c6497398b3fb9a6dde6a86 |
| رقم الأكسشن: | edsdoj.78de457c49c6497398b3fb9a6dde6a86 |
| قاعدة البيانات: | Directory of Open Access Journals |
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