دورية أكاديمية
RESULTS OF STAGED ENDOVASCULAR MYOCARDIAL REVASCULARISATION IN PATIENTS TREATED FOR ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION AND MULTIVESSEL DISEASE
| العنوان: | RESULTS OF STAGED ENDOVASCULAR MYOCARDIAL REVASCULARISATION IN PATIENTS TREATED FOR ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION AND MULTIVESSEL DISEASE |
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| المؤلفون: | Alexander V. Bocharov, Leonid V. Popov |
| المصدر: | Кубанский научный медицинский вестник, Vol 26, Iss 3, Pp 25-32 (2019) |
| بيانات النشر: | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | acute coronary syndrome, percutaneous coronary intervention, 3rd generation drug-eluting stent, coronary artery bypass surgery, Medicine |
| الوصف: | Aim. To evaluate the results of complete functional endovascular myocardial revascularisation which is performed early after stenting the culprit artery (within 90 days) with third-generation sirolimus-eluting stents in patients treated for acute coronary syndrome (ACS) with ST-segment elevation and multivessel disease. Materials and methods. We analysed the results of a 2-year follow-up treatment period of patients suffering from ACS with ST-segment elevation and multivessel disease who had undergone urgent stenting of culprit artery. Within 90 days after stenting, a complete functional endovascular myocardial revascularisation was performed using third-generation sirolimus-eluting stents. The efficacy and safety of the procedure was evaluated according to the non-inferiority criteria in comparison with the literature data on myocardial revascularisation by coronary artery bypass surgery. Results. In the course of follow-up treatment, 1 lethal myocardial infarction (after 18 months from complete revascularisation) and 2 non-lethal myocardial infarctions were registered. The symptoms of angina returned in 7 patients, 6 of whom had undergone unplanned re-revascularisation within 6 to 12 months following complete revascularisation. The MACCE rate was 0.143 [95% confidence interval: 0.0770; 0.2497]. Conclusion. In patients having ACS with ST-segment elevation and multivessel disease, endovascular myocardial revascularisation performed early after stenting the culprit artery is equivalent to coronary artery bypass surgery in terms of cardiovascular mortality rates, as well as incidence of non-fatal cardiovascular events. However, such an approach underperforms compared to coronary artery bypass surgery in terms of a composite endpoint of MACCE and the number of required re-interventions. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 1608-6228 2541-9544 79474004 |
| Relation: | https://ksma.elpub.ru/jour/article/view/1777; https://doaj.org/toc/1608-6228; https://doaj.org/toc/2541-9544 |
| DOI: | 10.25207/1608-6228-2019-26-3-00-25-32 |
| URL الوصول: | https://doaj.org/article/794740043b0049b99a88bd137b73487c |
| رقم الأكسشن: | edsdoj.794740043b0049b99a88bd137b73487c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16086228 25419544 79474004 |
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| DOI: | 10.25207/1608-6228-2019-26-3-00-25-32 |