دورية أكاديمية
Role of Epinephrine and Extracorporeal Membrane Oxygenation in the Management of Ischemic Refractory Ventricular Fibrillation
| العنوان: | Role of Epinephrine and Extracorporeal Membrane Oxygenation in the Management of Ischemic Refractory Ventricular Fibrillation |
|---|---|
| المؤلفون: | Jason A. Bartos, MD, PhD, Sebastian Voicu, MD, Timothy R. Matsuura, BA, Adamantios Tsangaris, MD, Georgios Sideris, MD, PhD, Brett A. Oestreich, MD, Stephen A. George, MD, PhD, Matthew Olson, MD, Kadambari Chandra Shekar, MS, Jennifer N. Rees, PhD, Kathleen Carlson, MD, Pierre Sebastian, BBME, Scott McKnite, BS, Ganesh Raveendran, MD, Tom P. Aufderheide, MD, Demetris Yannopoulos, MD |
| المصدر: | JACC: Basic to Translational Science, Vol 2, Iss 3, Pp 244-253 (2017) |
| بيانات النشر: | Elsevier, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Summary: Extracorporeal membrane oxygenation (ECMO) is used in cardiopulmonary resuscitation (CPR) of refractory cardiac arrest. The authors used a 2 à 2 study design to compare ECMO versus CPR and epinephrine versus placebo in a porcine model of ischemic refractory ventricular fibrillation (VF). Pigs underwent 5 min of untreated VF and 10 min of CPR, and were randomized to receive epinephrine versus placebo for another 35 min. Animals were further randomized to left anterior descending artery (LAD) reperfusion at minute 45 with ongoing CPR versus venoarterial ECMO cannulation at minute 45 of CPR and subsequent LAD reperfusion. Four-hour survival was improved with ECMO whereas epinephrine showed no effect. Key Words: advanced cardiopulmonary life support, cardiac arrest, cardiopulmonary resuscitation, ECMO, extracorporeal membrane oxygenation, ischemic refractory ventricular fibrillation, ST-segment elevation myocardial infarction, ventricular fibrillation |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2452-302X 61968099 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2452302X1730092X; https://doaj.org/toc/2452-302X |
| DOI: | 10.1016/j.jacbts.2017.02.003 |
| URL الوصول: | https://doaj.org/article/7c2883013b8b4a619680992c6d80c515 |
| رقم الأكسشن: | edsdoj.7c2883013b8b4a619680992c6d80c515 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 2452302X 61968099 |
|---|---|
| DOI: | 10.1016/j.jacbts.2017.02.003 |