دورية أكاديمية
Efficiency of radiotherapy during local hyperthermia in the treatment of laryngeal and laryngopharyngeal cancer
| العنوان: | Efficiency of radiotherapy during local hyperthermia in the treatment of laryngeal and laryngopharyngeal cancer |
|---|---|
| المؤلفون: | E. L. Choinzonov, I. O. Spivakova, M. R. Mukhamedov, Zh. A. Startseva, O. V. Cheremisina, I. G. Frolova, D. E. Kulbakin, P. V. Surkova |
| المصدر: | Опухоли головы и шеи, Vol 5, Iss 2, Pp 8-13 (2015) |
| بيانات النشر: | ABV-press, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | рак гортани, рак гортаноглотки, локальная гипертермия, дистанционная лучевая терапия, лечебный патоморфоз, эффективность лечения, выживаемость, установка для локальной и глубокой гипертермии, стандартный режим фракционирования дозы, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Cancer of the larynx and laryngopharynx, which is accessible to visual and instrumental examination, remains the most relevant and complicated problem among head and neck malignances as before. Investigations show that the incidence of cancer at these sites in Russia in the last decade has risen from 4.5 to 9.67 %. This is a severe and poor prognostic form of cancer, which is characterized by its nonspecific early clinical manifestations, complex anatomic and topographic structure, and a high rate of regional metastases. The mainstay of treatment for head and neck cancer involves 3 components: surgery, chemotherapy, and radiotherapy (RT), which are performed alone or in combination. The most commonly used technique is combined, frequently crippling due to organ-removing operations. The clinical introduction of current radio modifiers, local and deep hyperthermia systems, is a promising approach to improving the results of treatment, to enhancing the radiation damage of RT, and to achieving the tumor regression sufficient for surgical intervention without augmenting the early and late toxicity inherent in chemoradiation treatment. The results of the performed study of 35 patients with T2–3N0–2M0 laryngeal and laryngopharyngeal cancer proved the high efficiency of local hyperthermia in treating malignancies in this region during both preoperative (grades III– IV therapeutic pathomorphism) and radical beam RT. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2222-1468 2411-4634 |
| Relation: | https://ogsh.abvpress.ru/jour/article/view/152; https://doaj.org/toc/2222-1468; https://doaj.org/toc/2411-4634 |
| DOI: | 10.17650/2222-1468-2015-5-2-8-13 |
| URL الوصول: | https://doaj.org/article/7ccd2048acf840a787b307741ff0b7fb |
| رقم الأكسشن: | edsdoj.7ccd2048acf840a787b307741ff0b7fb |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22221468 24114634 |
|---|---|
| DOI: | 10.17650/2222-1468-2015-5-2-8-13 |