دورية أكاديمية
أعرض في EDS

Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings

التفاصيل البيبلوغرافية
العنوان: Dendritic Spines and Development: Towards a Unifying Model of Spinogenesis—A Present Day Review of Cajal's Histological Slides and Drawings
المؤلفون: Pablo García-López, Virginia García-Marín, Miguel Freire
المصدر: Neural Plasticity, Vol 2010 (2010)
بيانات النشر: Wiley, 2010.
سنة النشر: 2010
المجموعة: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
الوصف: Dendritic spines receive the majority of excitatory connections in the central nervous system, and, thus, they are key structures in the regulation of neural activity. Hence, the cellular and molecular mechanisms underlying their generation and plasticity, both during development and in adulthood, are a matter of fundamental and practical interest. Indeed, a better understanding of these mechanisms should provide clues to the development of novel clinical therapies. Here, we present original results obtained from high-quality images of Cajal's histological preparations, stored at the Cajal Museum (Instituto Cajal, CSIC), obtained using extended focus imaging, three-dimensional reconstruction, and rendering. Based on the data available in the literature regarding the formation of dendritic spines during development and our results, we propose a unifying model for dendritic spine development.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2090-5904
1687-5443
Relation: https://doaj.org/toc/2090-5904; https://doaj.org/toc/1687-5443
DOI: 10.1155/2010/769207
URL الوصول: https://doaj.org/article/7fd93716dee4494ba1168dfffc111c0b
رقم الأكسشن: edsdoj.7fd93716dee4494ba1168dfffc111c0b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20905904
16875443
DOI:10.1155/2010/769207