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Circulating endothelin-1 levels are positively associated with chronic kidney disease in women but not in men: a longitudinal study in the Vara-Skövde cohort

التفاصيل البيبلوغرافية
العنوان: Circulating endothelin-1 levels are positively associated with chronic kidney disease in women but not in men: a longitudinal study in the Vara-Skövde cohort
المؤلفون: Margareta I. Hellgren, Per-Anders Jansson, Hormoz Alayar, Ulf Lindblad, Bledar Daka
المصدر: BMC Nephrology, Vol 22, Iss 1, Pp 1-7 (2021)
بيانات النشر: BMC, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: Endothelin-1, Kidney disease, Gender, Epidemiology, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Abstract Background The vasoconstricting peptide endothelin-1 (ET-1) is associated with endothelial dysfunction. The aim of this paper was to investigate whether circulating ET-1 levels predicts chronic kidney disease (CKD) in a prospective population study. Methods In 2002–2005, 2816 participants (30–74 years) were randomly selected from two municipalities in South-Western Sweden and followed up in a representative sample of 1327 individuals after 10 years. Endothelin-1 levels were assessed at baseline. Outcome was defined as CKD stage 3 or above based on eGFR
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2369
Relation: https://doaj.org/toc/1471-2369
DOI: 10.1186/s12882-021-02525-5
URL الوصول: https://doaj.org/article/c810f39b3d8f4d2aba92936ef88e4aaa
رقم الأكسشن: edsdoj.810f39b3d8f4d2aba92936ef88e4aaa
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712369
DOI:10.1186/s12882-021-02525-5